Can You Take Macrobid With Famotidine And Pantoprazole?

In our latest question and answer, the pharmacist discusses taking Macrobid, Pepcid and Protonix together.

Question

I’m taking famotidine 40mg tablets and pantoprazole 40mg. Can I take nitrofurantoin mono/mac 100mg caps for UTI?

Asked by Anna On Jun 24, 2023

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Jun 27, 2023
Last updated May 07, 2024

Key points

  • There is no known interaction between any of the medications in question.

Quick Answer

There is no known interaction between Macrobid (Nitrofurantoin Monohydrate/Macrocrystals), Protonix (pantoprazole), and Pepcid (famotidine). They are considered safe to take together.

Detailed Answer

Nitrofurantoin Monohydrate/Macrocrystals, commonly known by the brand name Macrobid, is an antibiotic frequently prescribed for urinary tract infections (UTIs). It works by killing bacteria in the urinary tract.

Regarding the co-administration of Pepcid (famotidine), Protonix (pantoprazole), and Macrobid (Nitrofurantoin mono/Mac), they are all generally considered safe to take together.

Macrobid absorption is not significantly affected by stomach pH (which Pepcid and Protonix alter) and neither Protonix nor Pepcid affects the metabolism of Macrobid in any way.

It should be noted that studies have found that although Macrobid can be taken with or without food, taking it with food can help make it better tolerated. Just a helpful tidbit for you.

Final Words

I hope this answer helped! Thanks for reaching out!

References

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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