Can You Take Meloxicam And Advil Together?

In our latest question and answer, our pharmacist discusses whether or not it is safe to take meloxicam and Advil (ibuprofen) together.

Question

I wrote the other day about meloxicam and an interaction. I want to know now if it is okay to take meloxicam and Advil together.

Asked by Liza On Sep 26, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Sep 26, 2022
Last updated Apr 18, 2024

Key points

  • Advil (ibuprofen) and meloxicam should not be taken together. Both drugs are in the same class and combining them will increase the risk of side effects.

Answer

There is an interaction between meloxicam (generic for Mobic) and Advil (ibuprofen). Both drugs are NSAIDs, and taking both would be considered a therapeutic duplication, which increases the risk of side effects with little to no additional pain-relieving benefit.

Concerns Taking Both Together

As stated, Advil (ibuprofen) and meloxicam are in the same drug class and are classified as NSAIDs (non-steroidal anti-inflammatory drugs).

Combining multiple non-steroidal anti-inflammatory agents has the potential to increase the risk of adverse effects including:

  • Gastrointestinal bleeding
  • Kidney dysfunction
  • Increase in blood pressure
  • Increased risk of heart attack

Studies have not shown that taking two NSAIDs provides any benefit over single-agent therapy.

The only real exception to taking two NSAIDs together is when your doctor prescribes aspirin for cardioprotection. There may be cases where adding on an additional NSAID to aspirin for pain relief is warranted.

Alternatives

Instead of taking two NSAIDs, you should explore other options for pain relief, which include adjusting the dose of one NSAID or adding on an additional drug, such as Tylenol (acetaminophen).

Final Words

Thanks for reaching out to us! Please do so again anytime.

References

  • Nonsteroidal anti-inflammatory drugs and upper and lower gastrointestinal mucosal damage., PubMed
  • Meloxicam Monograph, PubChem
  • Ibuprofen Monograph, PubChem
  • NSAID use selectively increases the risk of non-fatal myocardial infarction: a systematic review of randomised trials and observational studies., PubMed

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

Recent Questions