Difference Between Ozempic 1mg Per Dose Pen And Ozempic 2mg Per Dose Pen
In our latest question and answer, the pharmacist discusses the difference in drug concentration between two different Ozempic pens.

Question
How can the Ozempic 1 mg pen and the 2 mg pen be the same size and appear to have to same amount of medication?

Answered by Dr. Brian Staiger, PharmD
Medical Content Reviewed By HelloPharmacist
Staff
Last updated Apr 08, 2025
Key points
- The 1mg dose and 2mg dose Ozempic pens contain the same volume of liquid (3mL per pen), but the 2mg pen has a higher drug concentration. The 1mg pen has a concentration of 4mg of drug per 3mL, while the 2mg pen has a concentration of 8mg of drug per 3mL.
- This means that whether you inject 1mg from the 1mg pen or 2mg from the 2mg pen, you're injecting the same volume of liquid (approximately 0.746 mL) into your body.
Answer
Great question! Thanks for reaching out. You are correct that the Ozempic 1mg dose pen and the 2mg dose pen contain the same volume (3mL per pen). However, the 2mg dose pen is a higher concentration. I've got images of the packaging below that demonstrate this.
As you can see in the above images:
- The 1mg per dose Ozempic pen contains a total of 3mL. The concentration of the pen is 4mg of drug per 3mL (or 4mg/3mL).
- The 2mg per dose Ozempic pen also contains a total of 3mL. The concentration of the pen is 8mg of drug per 3mL (or 8mg/3mL).
So, even though the two different pens are the same 'size' (i.e., contain the same volume of liquid), they are different concentrations.
In fact, based on the concentration of these pens, regardless of whether or not you are injecting 1mg (from the 1mg per dose pen) or the 2mg (from the 2mg per dose pen), you are injecting the same volume of liquid into your body (which comes out to around 0.746 mL).
Final Words
I hope you found this answer helpful!
Thank you!
References
- Ozempic Prescribing Information, AccessFDA
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Dr. Brian Staiger, PharmD
- 3850 views