Help! I Accidentally Took Four Advil Tablets

In our latest question and answer, our pharmacist discusses the concerns an individual has after accidentally taking 4 Advil tablets.

Question

I accidentally took 4 Advil when I meant to only take two. I literally was just in mindless mode and took 2 right after I had just taken 2. Am I going to be okay? If 4 safe?

Asked by Susan On Jan 26, 2023

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Jan 26, 2023
Last updated Apr 26, 2024

Key points

  • Accidentally taking 4 tablets of Advil (800mg) is still within a generally considered safe dosage range, however, it's important to note that taking higher doses of ibuprofen can increase the risk of side effects, especially if taken over long periods of time or if you have pre-existing medical conditions.
  • Doses over 400mg of ibuprofen, or taking ibuprofen for more than a couple of weeks in a row, should be under the supervision of a doctor.

Answer

Thanks for reaching out and I certainly understand your concern here!

While you did take more Advil (ibuprofen) than is recommended at one time if you are self-treating a condition (i.e, not under the supervision of a doctor), the dose you took (800mg) is actually still within the maximum dosing limits of the drug and if you are otherwise healthy, is considered a relatively safe dosage, so I wouldn't be too worried here.

Over-The-Counter And Prescription Ibuprofen Have Different Dosing Recommendations

Ibuprofen is an NSAID (non-steroidal anti-inflammatory drug) that is available as both a prescription drug and an over-the-counter drug.

It's important to know that over-the-counter (OTC) ibuprofen has different dosing recommendations compared to prescription ibuprofen. OTC ibuprofen is intended for short-term use of lower, less severe levels of pain, while prescription ibuprofen may be used for longer periods of time, at higher doses, under the guidance of a healthcare provider.

  • The recommended dosage for OTC Ibuprofen: 200-400mg every four to six hours. Maximum daily dosage 1,200mg.
  • The recommended dosage for Prescription Ibuprofen: Up to 800mg every four to six hours. Maximum daily dosage 3,200mg.

The dosage recommendations for ibuprofen are all about patient safety as high doses, taken over an extended period of time, are associated with a greater risk of side effects.

Is 4 Advil Tablets (800mg Ibuprofen) Too Much At One Time?

Let's circle back to your question where you said you took 4 tablets of Advil, which equals 800mg of ibuprofen, and are worried this is too much.

Again, I wouldn't recommend taking that much if you are self-treating a condition not under the supervision of a doctor but you still did take a dose that is within the FDA-approved dosing for the drug, so I wouldn't really consider this an overdose. If you are otherwise healthy and don't have any conditions that could be exacerbated by ibuprofen (like stomach ulcers), it is unlikely you will experience any serious negative side effects.

As mentioned, higher doses of ibuprofen, taken over a long period of time, are associated with more side effects. So, just to provide some context here when I talk about side effects, the following are associated with high doses of ibuprofen when taken over long periods of time:

  • Gastrointestinal (GI) problems: High doses or long-term use of NSAIDs can increase the risk of stomach ulcers, bleeding, and perforation of the stomach or intestines.
  • Kidney problems: Long-term use of NSAIDs can lead to kidney damage. People with existing kidney problems are at increased risk.
  • Cardiovascular issues: There is evidence that high doses or long-term use of certain NSAIDs may increase the risk of heart attacks and strokes.

I want to reiterate that accidentally taking a one-time dose of 800mg ibuprofen (4 Advil) tablets likely won't cause you any problems (like the ones mentioned above) outside the possibility of some mild side effects, like stomach pain, as that dosage is still within a generally considered safe range

I know you said it was an accident, but if you find yourself needing more than 2 tablets of Advil at one time (400mg), or you need to take it consistently for weeks, please see a doctor so you can be appropriately evaluated and monitored.

Final Words

Thanks again for contacting us and I hope you found this helpful!

References

  • Ibuprofen Monograph, PubChem
  • Motrin Prescribing Information, AccessFDA
  • Recognizing the Risks of Chronic Nonsteroidal Anti-Inflammatory Drug Use in Older Adults, PubMed

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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