How Many Times A Day Can You Take Claritin (Loratadine)?

In our latest question and answer, the pharmacist discusses how many times per day you can safely take Claritin (loratadine).

Question

How many times per day can you take Claritin (loratadine)? I feel that sometimes it doesn't last all day.

Asked by Beauty On May 20, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published May 20, 2022
Last updated Apr 20, 2024

Key points

  • Claritin (loratadine) is generally dosed once daily (every 24 hours) but lower doses can be taken twice daily.

Claritin (loratadine) is a second-generation antihistamine and is most commonly dosed as 10 mg once daily (every 24 hours).

However, it is also available in 5 mg dosage forms, which can be taken twice daily (every 12 hours).

So, overall, any Claritin product that is 10 mg should only be taken once a day. Any product that is 5 mg can be taken twice a day.

The only exception to this is for adolescents between 2 and 6 years old. For this age group, 5 mg is the maximum daily dose and it should only be taken once daily (every 24 hours).

Claritin (loratadine) Dosing Based On Age

  • Ages 2 to 6: 5mg once every 24 hours.
  • Ages 6 and over (including adults): 10mg once every 24 hours OR 5mg every 12 hours.

Below is the list of Claritin products and their indicated doses for ages 6 and older:

  • Claritin 10mg tablets (one tablet every 24 hours)
  • Claritin 5mg RediTabs (one tablet every 12 hours or 2 tablets every 24 hours)
  • Claritin 10mg RediTabs (one tablet every 24 hours)
  • Claritin-D 12 Hour (one tablet every 12  hours)
  • Claritin-D 24 Hour (one tablet every 24 hours)
  • Claritin Chewables 5mg (one tablet every 12 hours or two tablets every 24 hours)
  • Claritin Syrup (one teaspoon every 24 hours)

Higher Doses

Although the maximum daily dose for loratadine approved by the FDA is 10mg, some studies show that higher doses can be safe and effective.

One study reported that 40mg per day (four times the recommended dose) was effective at treating severe itching and rashes, with minimal side effects. The study concluded:

Up-dosing antihistamines higher than fourfold dosage seems a feasible therapeutic option with regards to effectiveness and safety. The need for third line therapies could be decreased by 49%, with a very limited increase of reported side effects.
Effectiveness and safety of antihistamines up to fourfold or higher in treatment of chronic spontaneous urticaria. Clin Transl Allergy 7, 4 (2017).

So, higher doses of Claritin may be an option for some people, especially if you feel it is not lasting over 24 hours per dose, but you should not take over 10mg daily without speaking to your doctor.

Additional Information

If you feel Claritin isn't working for a full 24 hours, it isn't recommended to increase the dose over 10 mg without first consulting with your doctor.

A better option may be to add a different class of medication on top of your daily Claritin for best allergy control. Options include:

  • Nasal corticosteroids (e.g. Flonase, Nasacort)
  • Mast cell stabilizer (e.g. Cromolyn nasal spray)

Both of the above options can help better control your allergy symptoms.

Thanks again for your question!

References

  • Effectiveness and safety of antihistamines up to fourfold or higher in treatment of chronic spontaneous urticaria, Clinical and Translational Allergy
  • Loratadine (Clarityn), NHS
  • Loratadine Monograph, PubChem
  • Loratadine (SCH29851) 40 mg Once Daily versus Terfenadine 60 mg Twice Daily in the Treatment of Seasonal Allergic Rhinitis, SagePub

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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