Is Horny Goat Weed Safe To Take With Strattera (Atomoxetine)?
In our latest question and answer, the pharmacist discusses the combined use of Horny Goat Weed and Strattera (atomoxetine).
Question
Can you take Horny Goat Weed with Strattera 80 mg (for ADD/ADHD)?
Answered by Dr. Brian Staiger, PharmD
Medical Content Reviewed By HelloPharmacist
Staff
Last updated Jan 24, 2025
Answer
Hello, and thank you for reaching out to us with your question!
Our very own drug-supplement interaction checker indicates that there are no known interactions between horny goat weed and Strattera (Horny Goat Weed - Atomoxetine Interaction Details | HelloPharmacist).
However, it's important to note that this doesn't necessarily mean an interaction is impossible. There is often limited research on traditional supplements like horny goat weed and how they might interact with prescription medications.
More Detail
Horny goat weed contains several active compounds, including flavonoids and phytoestrogens, and may theoretically affect drugs metabolized by enzymes such as CYP1A2, CYP2B6, and CYP3A4. If you look at our detail page for Horny Goat Weed (Horny Goat Weed herbal information | HelloPharmacist), you'll see we do have plenty of interactions listed (just not with atomoxetine).
Atomoxetine is primarily metabolized via CYP2D6, which horny goat weed is not thought to affect in a clinically significant way.
Regardless, it is still wise to check with your healthcare provider before adding it to your regimen so you can be appropriately monitored.
Final Words
Thanks again for reaching out, and please feel free to do so again anytime!
- Dr. Brian Staiger, PharmD
- 1722 views