Is Horny Goat Weed Safe To Take With Strattera (Atomoxetine)?

In our latest question and answer, the pharmacist discusses the combined use of Horny Goat Weed and Strattera (atomoxetine).

Question

Can you take Horny Goat Weed with Strattera 80 mg (for ADD/ADHD)?

Asked by Kris On Sep 05, 2024

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Sep 05, 2024
Last updated Jan 24, 2025

Answer

Hello, and thank you for reaching out to us with your question!

Our very own drug-supplement interaction checker indicates that there are no known interactions between horny goat weed and Strattera (Horny Goat Weed - Atomoxetine Interaction Details | HelloPharmacist).

However, it's important to note that this doesn't necessarily mean an interaction is impossible. There is often limited research on traditional supplements like horny goat weed and how they might interact with prescription medications.

More Detail

Horny goat weed contains several active compounds, including flavonoids and phytoestrogens, and may theoretically affect drugs metabolized by enzymes such as CYP1A2, CYP2B6, and CYP3A4. If you look at our detail page for Horny Goat Weed (Horny Goat Weed herbal information | HelloPharmacist), you'll see we do have plenty of interactions listed (just not with atomoxetine).

Atomoxetine is primarily metabolized via CYP2D6, which horny goat weed is not thought to affect in a clinically significant way.

Regardless, it is still wise to check with your healthcare provider before adding it to your regimen so you can be appropriately monitored.

Final Words

Thanks again for reaching out, and please feel free to do so again anytime!

References

  • Strattera Prescribing Information, AccessFDA
  • The potential of Epimedium koreanum Nakai for herb-drug interaction, PubMed

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

Recent Questions