Is It Safe To Take Magnesium And Melatonin Together?

Answer

Thanks for reaching out to us Joe!

There are no known interactions between magnesium and melatonin. They can safely be taken together.

In fact, there are a number of products on the market that contain both magnesium and melatonin as several studies have reported that the combination can help improve sleep compared to either alone. These studies have also reported that magnesium supplementation increases melatonin levels (which is one reason why magnesium may help improve sleep).

What Do The Studies Say?

As mentioned, several studies have shown positive benefits for the treatment of insomnia using melatonin and magnesium.

Magnesium supplementation in some individuals seems to raise melatonin levels, and studies in which individuals supplemented with both showed improved sleep metrics.

One such study reported the following regarding magnesium supplementation:

As compared to the placebo group, in the experimental group, dietary magnesium supplementation brought about statistically significant increases in sleep time, sleep efficiency, concentration of serum renin, and melatonin, and also resulted in significant decrease of ISI score, sleep onset latency and serum cortisol concentration.

Another study, testing a combination of zinc, magnesium, and melatonin, reported the following results:

The administration of nightly melatonin, magnesium, and zinc appears to improve the quality of sleep and the quality of life in long-term care facility residents with primary insomnia.

Now, more larger-scale studies are needed to better understand where melatonin and magnesium supplementation could fit in for the treatment of insomnia, but, going back to your question, there is no evidence to suggest they interact or interfere with one another.

Final Words

Thanks again for reaching out and please feel free to do so again in the future!