Is It Safe To Use Amoxicillin And Hyland's Kids Cold & Cough Together?
In our latest question and answer, the pharmacist discusses whether or not there is a drug interaction between amoxicillin and Hyland's cough syrup.

Question
Is it safe to give Hyland's Kids Cough & Cold with amoxicillin?

Answered by Dr. Brian Staiger, PharmD
Medical Content Reviewed By HelloPharmacist
Staff
Last updated May 13, 2025
Key points
- There is no known interaction between amoxicillin and Hyland's Naturals Kids Cold & Cough.
Answer
Thanks so much for reaching out! We love answering questions like this so please feel free to always reach out when something like this comes up for you.
Getting into your question, there is no known drug interaction between Hyland's Kids Cough & Cold and amoxicillin. They are considered safe to take together.
Hyland's Kids Cold & Cough is a homeopathic product, and homeopathic products generally don't have a risk of drug interactions due to the very small amounts of active ingredients used in them (although this isn't always the case as some homeopathic products [e.g., Cold-Eeze) do contain enough active ingredients to interact with some drugs).
What Is In Hyland's 4Kids Cold & Cough?
The specific ingredients contained in Hyland's 4Kids Cold & Cough are:
- Allium Cepa 6X
- Hepar Sulph Calc 12X
- Hydrastis 6X
- Natrum Muriaticum 6X
- Phosphorus 12X
- Pulsatilla 6X
- Sulphur 12X
Homeopathic products are based on the principle of 'like cures like". They contain ingredients that are highly diluted, which in larger amounts, would cause the symptoms that are being treated.
For example, in homeopathy, a runny nose would be treated with a very small amount of something that would normally cause a runny nose, like an onion. Hyland's 4Kids Cold & Cough contains Allium Cepa, which is an extract obtained from onions.
All of the ingredients in Hyland's 4Kids Cold & Cough are homeopathic and highly diluted. There is nothing in it that is known to interact with amoxicillin. You can feel safe combining them.
Final Words
I imagine you asked your question because your child is sick and, in addition to using amoxicillin to treat a bacterial infection, you are looking to provide additional symptom relief. As mentioned, Hyland's 4Kids Cold & Cough is safe to use, and I hope it helps your child feel better.
Thanks again for reaching out!
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Dr. Brian Staiger, PharmD
- 8300 views