Is Tylenol Safe To Take With Entocort (Budesonide)?

In our latest question and answer, our pharmacist discusses whether or not there is an interaction between Entocort and acetaminophen.


Can you take Entocort EC and Tylenol Arthritis medications together?

Asked by Zoe On Aug 23, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Aug 24, 2022
Last updated Aug 24, 2022

Key points

  • There is no known drug interaction between Tylenol Arthritis and Entocort EC.


Hi Zoe and thanks for reaching out!

There is no known drug interaction between Entocort (budesonide) and Tylenol Arthritis (acetaminophen extended-release). They are safe to take together.

Assuming for are taking Entocort for Crohn's disease, Tylenol (acetaminophen) is generally a safer choice than other pain relievers, like ibuprofen or naproxen, as it has fewer gastrointestinal side effects.

About Entocort

Entocort EC (budesonide) is used to treat Crohn's disease (a condition in which the body attacks the lining of the digestive tract, causing pain, diarrhea, weight loss, and fever).

Entocort EC is in a class of medications called corticosteroids. It works by decreasing inflammation (swelling) in the digestive tract of people who have Crohn's disease or in the kidney of people with nephropathy.

About Tylenol

Tylenol (acetaminophen) is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever. acetaminophen may also be used to relieve the pain of osteoarthritis (arthritis caused by the breakdown of the lining of the joints).

Tylenol (acetaminophen) is in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers). It works by changing the way the body senses pain and by cooling the body. Tylenol Arthritis is an extended-release form of acetaminophen.

Final Words

Thanks again for your question and please feel free to reach out again in the future!


About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 11 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Feel free to send him an email at! You can also connect with Dr. Brian Staiger on LinkedIn.

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