Maty's Children's Nighttime Cough Syrup With Genexa Kids Allergy
In our latest question and answer, our pharmacist discusses whether or not combining Maty's Children's Nighttime Cough Syrup With Genexa Kids Allergy is safe.
Is there an interaction between Matys Nighttime Cough Syrup for kids and Genexa Kids Allergy medicine?
Dec 28, 2022- There is no known interaction between Maty's Nighttime Cough Syrup and Genexa Kids Allergy, and they are likely safe to use together.
- Using both products together will cause more sedation than using either one alone since both contain sedating ingredients.
Answer
Thanks for reaching out! Although it can be a challenge to definitively determine whether or not herbal/natural ingredients interact with over-the-counter or prescription drugs due to the lack of available data, there is nothing to suggest that Maty's Nighttime Cough Syrup interacts with Genexa Kids Allergy.
Combining both will likely cause more sedation than either used alone since they both contain sedating ingredients, but aside from that, they are most likely safe to use together.
In the next sections, I go into the ingredients of each of these products.
What Is In Maty's Nighttime Cough Syrup?

Maty's Nighttime Cough Syrup contains the following ingredients:
- Honey Blend (Clover, Buckwheat)
- Elderberry Fruit Extract
- Aronia Berry
- Acerola Cherry Extract
- Chamomile Leaves
- Apple Cider Vinegar
- Water
- Sea Salt
- Lemon Balm Leaf Extract
- Nutmeg Seed
- Zinc Gluconate
- Citric Acid
- Apricot Pit Extract
There is certainly some evidence that some of these ingredients (such as elderberry and nutmeg) may interact with traditional drugs, but they are used in this product in low amounts and, overall, they are all generally considered safe to take.
What Is In Genexa Kids Allergy?

Genexa, as a brand, markets 'clean' products as they strive to avoid containing artificial ingredients, dyes, or other 'fillers'. Most Genexa products do, however, use common drugs, such as acetaminophen (generic of Tylenol) and calcium carbonate (generic of Tums).
Genexa Kids' Allergy is a product that contains diphenhydramine, which is the active ingredient in Benadryl. In addition to the active ingredient of diphenhydramine, this product contains:
- Organic agave syrup
- Natural citrus extract
- Purified water
Diphenhydramine is a sedating antihistamine and a very common ingredient in nighttime cough/cold and allergy medications. There is plenty of data available regarding what drugs it interacts with.
While there is no specific interaction between the diphenhydramine contained in Genexa Kids' Allergy and the herbal ingredients in Maty's Nighttime Cough Syrup, both will cause sedation.
Diphenhydramine is well known to be quite sedating, which is why it is often used as a sleep aid. Maty's Nighttime Cough Syrup contains several ingredients intended to cause sedation, such as lemon balm extract and chamomile.
So, if you combine Genexa Kids Allergy with Maty's Nighttime Cough Syrup, expect your child to experience drowsiness and sedation. Aside from that, there is no data to suggest any drug interactions.
Final Words
Thanks for reaching out and I hope your child starts to feel better soon.
References & sources
- Diphenhydramine Monograph — PubChem
- Genexa Kids Allergy Product Page — Genexa
- Maty's Nighttime Cough Syrup Product Page — Maty's Health
Glossary — Terms in This Answer
- Herbal/natural ingredients
- Substances derived from plants and other natural sources used in medicines and supplements.
- Over-the-counter drugs
- Medications you can buy without a prescription from a pharmacist or store.
- Prescription drugs
- Medications that require a doctor's authorization and written order to obtain.
- Sedating ingredients
- Substances that cause drowsiness or promote sleep.
- Antihistamine
- A drug that reduces or blocks histamine, a chemical released during allergic reactions.
- Diphenhydramine
- A common antihistamine medication used to treat allergies and is often used as a sleep aid.
- Drug interactions
- When two or more medicines affect each other's effectiveness or cause harmful effects when taken together.
- Sedation
- A state of reduced alertness and drowsiness caused by certain medications.