Maty's Children's Nighttime Cough Syrup With Genexa Kids Allergy

In our latest question and answer, our pharmacist discusses whether or not combining Maty's Children's Nighttime Cough Syrup With Genexa Kids Allergy is safe.

2 min read Updated Jun 2026 Read by 740 people
Maty's Children's Nighttime Cough Syrup With Genexa Kids Allergy
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Brit asked

Is there an interaction between Matys Nighttime Cough Syrup for kids and Genexa Kids Allergy medicine?

Dec 28, 2022
The quick answer
  • There is no known interaction between Maty's Nighttime Cough Syrup and Genexa Kids Allergy, and they are likely safe to use together.
  • Using both products together will cause more sedation than using either one alone since both contain sedating ingredients.
A quick summary of Dr. Brian Staiger, PharmD's full answer below, condensed by AI from that answer only (not from any outside source). The pharmacist's answer is the source of record.
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Answer

Thanks for reaching out! Although it can be a challenge to definitively determine whether or not herbal/natural ingredients interact with over-the-counter or prescription drugs due to the lack of available data, there is nothing to suggest that Maty's Nighttime Cough Syrup interacts with Genexa Kids Allergy.

Combining both will likely cause more sedation than either used alone since they both contain sedating ingredients, but aside from that, they are most likely safe to use together.

In the next sections, I go into the ingredients of each of these products.

What Is In Maty's Nighttime Cough Syrup?

Matys Nighttime Cough Syrup

Maty's Nighttime Cough Syrup contains the following ingredients:

  • Honey Blend (Clover, Buckwheat)
  • Elderberry Fruit Extract
  • Aronia Berry
  • Acerola Cherry Extract
  • Chamomile Leaves
  • Apple Cider Vinegar
  • Water
  • Sea Salt
  • Lemon Balm Leaf Extract
  • Nutmeg Seed
  • Zinc Gluconate
  • Citric Acid
  • Apricot Pit Extract

There is certainly some evidence that some of these ingredients (such as elderberry and nutmeg) may interact with traditional drugs, but they are used in this product in low amounts and, overall, they are all generally considered safe to take.

What Is In Genexa Kids Allergy?

Genexa Kids Allergy

Genexa, as a brand, markets 'clean' products as they strive to avoid containing artificial ingredients, dyes, or other 'fillers'. Most Genexa products do, however, use common drugs, such as acetaminophen (generic of Tylenol) and calcium carbonate (generic of Tums).

Genexa Kids' Allergy is a product that contains diphenhydramine, which is the active ingredient in Benadryl. In addition to the active ingredient of diphenhydramine, this product contains:

  • Organic agave syrup
  • Natural citrus extract
  • Purified water

Diphenhydramine is a sedating antihistamine and a very common ingredient in nighttime cough/cold and allergy medications. There is plenty of data available regarding what drugs it interacts with.

While there is no specific interaction between the diphenhydramine contained in Genexa Kids' Allergy and the herbal ingredients in Maty's Nighttime Cough Syrup, both will cause sedation.

Diphenhydramine is well known to be quite sedating, which is why it is often used as a sleep aid. Maty's Nighttime Cough Syrup contains several ingredients intended to cause sedation, such as lemon balm extract and chamomile.

So, if you combine Genexa Kids Allergy with Maty's Nighttime Cough Syrup, expect your child to experience drowsiness and sedation. Aside from that, there is no data to suggest any drug interactions.

Final Words

Thanks for reaching out and I hope your child starts to feel better soon.

References & sources
  1. Diphenhydramine Monograph — PubChem
  2. Genexa Kids Allergy Product Page — Genexa
  3. Maty's Nighttime Cough Syrup Product Page — Maty's Health
Glossary — Terms in This Answer
Herbal/natural ingredients
Substances derived from plants and other natural sources used in medicines and supplements.
Over-the-counter drugs
Medications you can buy without a prescription from a pharmacist or store.
Prescription drugs
Medications that require a doctor's authorization and written order to obtain.
Sedating ingredients
Substances that cause drowsiness or promote sleep.
Antihistamine
A drug that reduces or blocks histamine, a chemical released during allergic reactions.
Diphenhydramine
A common antihistamine medication used to treat allergies and is often used as a sleep aid.
Drug interactions
When two or more medicines affect each other's effectiveness or cause harmful effects when taken together.
Sedation
A state of reduced alertness and drowsiness caused by certain medications.
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Dr. Brian Staiger, PharmD
About the pharmacist

Dr. Brian Staiger, PharmD

Clinical Pharmacy

Doctor of Pharmacy, board certified clinical pharmacist (BCPS), American Herbalist Guild, Medication Therapy Management certified

Brian Staiger, PharmD, BCPS, is a licensed pharmacist with more than 13 years of experience across retail pharmacy, clinical pharmacy, medication safety, pharmacy program development, and healthcare administration. He is the founder of HelloPharmacist.com, where he helps patients...

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