Can You Take Mucinex Multi-Symptom With Ibuprofen?

Answer

Yes, Mucinex Multi-Symptom for children can be taken with ibuprofen as there is no reported or listed interaction. 'Original' Mucinex, which only contains guaifenesin, is also safe to take with ibuprofen.

However, it is important to note that there are a few different Mucinex Multi-Symptom products. Two already contains an analgesic, acetaminophen (generic of Tylenol). Generally, it is not recommended to use the analgesics at the same time (acetaminophen and ibuprofen) but there are situations where this is okay, and may even be recommended by your doctor.

Below are the ingredients for each Mucinex Multi-Symptom product:

Mucinex Multi-Symptom Cold

• Dextromethorphan (cough suppressant)

• Guaifenesin (expectorant)

• Phenylephrine (nasal decongestant)

Mucinex Multi-Symptom Cold Night Time Formula

• Acetaminophen (pain reliever)

• Phenylephrine (nasal decongestant)

• Diphenhydramine (sedating antihistamine)

Mucinex Multi-Symptom Cold & Fever

• Acetaminophen (pain reliever)

• Phenylephrine (nasal decongestant)

• Dextromethorphan (cough suppressant)

• Guaifenesin (expectorant)

Final Words

Mucinex Multi-Symptom Cold is the only product that does not already contain acetaminophen. If you are using that product, ibuprofen is fine to give at the same time. If you are using the other products, that contain acetaminophen, it would be prudent to wait 1 to 2 hours after dosing those to give ibuprofen unless otherwise directed by your doctor.