What Is The Difference Between Cataflam And Voltaren?

In our latest question and answer, the pharmacist discusses the difference between Cataflam and Voltaren.

3 min read Updated Jun 2026 Read by 10,264 people
What Is The Difference Between Cataflam And Voltaren?
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Tracnmud59 asked

Can you describe the difference between Cataflam and Voltaren? Thanks!

Oct 21, 2022
The quick answer
  • Cataflam contains diclofenac potassium and may work faster than Voltaren, which contains diclofenac sodium, because it absorbs more quickly and reaches peak levels in about an hour compared to 2.3 hours for Voltaren.
  • Voltaren comes in more strengths and formulations including gels, eye drops, and extended-release tablets, while Cataflam is only available as an immediate-release 50mg tablet.
  • Diclofenac sodium (Voltaren) is significantly less expensive than diclofenac potassium (Cataflam) when comparing the same dose.
A quick summary of Dr. Brian Staiger, PharmD's full answer below, condensed by AI from that answer only (not from any outside source). The pharmacist's answer is the source of record.
Medications in this answer — tap to explore

Answer

Hi and thanks for writing to us! While these two drugs aren’t very different, they both contain diclofenac after all, there are a few differences between them.

Voltaren And Cataflam Are Different Forms Of Diclofenac

First and foremost, Voltaren is the brand name of the drug Diclofenac Sodium. Cataflam is the brand name of Diclofenac Potassium.

Diclofenac needs to be bound to a molecule like sodium or potassium in order for you to absorb them. While the molecule a drug is attached to can alter some of the chemical properties of the compound, it's not very common that it makes a significant clinical difference. Having said this, there often is at least some difference.

For example, studies suggest that Cataflam (diclofenac potassium) may work slightly faster than Voltaren (diclofenac sodium) since it is absorbed more quickly.

In case you're wondering what some other examples are of drugs that are available in different salt forms, here are a few:

  • Wellbutrin XL (bupropion hydrochloride) and Aplenzin (bupropion hydrobromide)
  • Calcium supplements (e.g. calcium carbonate, calcium citrate)
  • Doxycycline hyclate and doxycycline monohydrate
  • Toprol XL (metoprolol succinate) and Lopressor (metoprolol tartrate)

Different Strengths Available

Next are the different strengths and formulations that exist.

Cataflam is only available in one strength, an immediate release 50mg tablet. Voltaren is available in several more strengths and formulations, a gel, an eye drop, 25mg, 50mg, and 75mg enteric coated tablets, and a 100mg extended release tablet.

You might be wondering what is the difference between the oral formulations of both medications. As mentioned in the section above, Cataflam may absorb faster than Voltaren, and thus, work faster.

Additionally, Cataflam is an immediate release tablet. It gets broken down and dissolved in your stomach, then absorbed in the beginning of your small intestine. It is absorbed relatively quickly and reaches its peak concentration in your blood in about an hour.

Voltaren is an enteric coated and has a special coating on the tablets which only dissolves in the basic upper region of the small intestine, so it avoids being dissolved in the stomach. It might cause less stomach irritation because of this, but is also absorbed slower, reaching peak blood concentration after about 2.3 hours.

Price Differences

Lastly, there is a difference in price. While both medications are covered by the majority of commercial insurance plans, diclofenac potassium is over two times more expensive than diclofenac sodium when comparing a 50mg dose. Again, neither medication is overly expensive, but if price is a big concern, I would recommend diclofenac sodium.

Final Words

I hope this helps to clear up any confusion. Feel free to write us again in the future!

References & sources
  1. Cataflam Prescribing Information — AccessFDA
  2. Voltaren Prescribing Information — AccessFDA
  3. Diclofenac Potassium Monograph — PubChem
  4. Diclofenac Sodium Monograph — PubChem
Glossary — Terms in This Answer
Diclofenac
A nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation.
Brand name
The commercial name given to a drug by the manufacturer, as opposed to its chemical name.
Salt form
A drug chemically combined with another molecule (like sodium or potassium) to make it absorbable by the body.
Immediate release
A medication formulation that dissolves and releases the drug quickly into your bloodstream.
Enteric coated
A special coating on a tablet that prevents it from dissolving in the stomach and instead dissolves in the small intestine.
Peak concentration
The highest level of a drug present in your blood after you take a dose.
Extended release
A medication formulation designed to release the drug slowly over a longer period of time.
Absorption
The process by which a drug enters the bloodstream from the digestive system or other parts of the body.
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Dr. Brian Staiger, PharmD
About the pharmacist

Dr. Brian Staiger, PharmD

Clinical Pharmacy

Doctor of Pharmacy, board certified clinical pharmacist (BCPS), American Herbalist Guild, Medication Therapy Management certified

Brian Staiger, PharmD, BCPS, is a licensed pharmacist with more than 13 years of experience across retail pharmacy, clinical pharmacy, medication safety, pharmacy program development, and healthcare administration. He is the founder of HelloPharmacist.com, where he helps patients...

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