Conjugated Linoleic Acid (cla) - Plavix (Clopidogrel) Interaction
Herbal: Conjugated Linoleic Acid (cla)
Drug: Clopidogrel
Brand names:
Plavix
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
Clopidogrel is classified as belonging to the following category: Anticoagulant/Antiplatelet Drugs
Theoretically, CLA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Some clinical evidence suggests that intake of CLA reduces platelet aggregation by approximately 10%. The clinical significance of this effect is unclear.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Sofi, F., Buccioni, A., Cesari, F., Gori, A. M., Minieri, S., Mannini, L., Casini, A., Gensini, G. F., Abbate, R., and Antongiovanni, M. Effects of a dairy product (pecorino cheese) naturally rich in cis-9, trans-11 conjugated linoleic acid on lipid, inf
Conjugated Linoleic Acid (cla) Overview
Conjugated linoleic acid (CLA) is a type of polyunsaturated fatty acid found in small amounts in the meat and dairy products of certain animals. It is also found in small amounts in some plant-based oils, such as safflower and sunflower oil. The majority of dietary supplements utilize CLA obtained from safflower oil.
CLA has been the subject of numerous scientific studies and has been suggested to have a number of potential health benefits, including weight loss, improving body composition, reducing inflammation, and decreasing the risk of certain types of cancer. However, the evidence for these potential benefits is mixed and more research is needed to fully understand the effects of CLA on health.
Clopidogrel Overview
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Clopidogrel is used alone or with aspirin to prevent serious or life-threatening problems with the heart and blood vessels in people who have had a stroke, heart attack, or severe chest pain. This includes people who have percutaneous coronary intervention (PCI; angioplasty; a type of heart surgery) that may involve inserting coronary stents (metal tubes surgically placed in clogged blood vessels to improve blood flow) or who have coronary artery bypass grafting (CABG; a type of heart surgery). Clopidogrel is also used to prevent serious or life-threatening problems with the heart and blood vessels in people who have peripheral arterial disease (poor circulation in the blood vessels that supply blood to the legs). Clopidogrel is in a class of medications called antiplatelet medications. It works by preventing platelets (a type of blood cell) from collecting and forming clots that may cause a heart attack or stroke.
Conjugated Linoleic Acid (cla) - More Interactions
Conjugated Linoleic Acid (cla) interacts with 283 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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