Clopidogrel

Generic name: Pronounced as (kloh pid' oh grel)
Brand names
  • Plavix®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 12/15/2020

Clopidogrel must be changed to an active form in your body so that it can treat your condition. Some people do not change clopidogrel to its active form in the body as well as other people. Because the medication does not work as well in these people, they may be at a higher risk of having a heart attack or stroke. There are tests available to identify people who have trouble changing clopidogrel to an active form. Talk to your doctor about whether you should be tested. If you are found to have difficulty converting clopidogrel to its active form, your doctor may change your dose of clopidogrel or tell you not to take clopidogrel.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with clopidogrel and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.

Talk to your doctor about the risks of taking clopidogrel.

Clopidogrel is used alone or with aspirin to prevent serious or life-threatening problems with the heart and blood vessels in people who have had a stroke, heart attack, or severe chest pain. This includes people who have percutaneous coronary intervention (PCI; angioplasty; a type of heart surgery) that may involve inserting coronary stents (metal tubes surgically placed in clogged blood vessels to improve blood flow) or who have coronary artery bypass grafting (CABG; a type of heart surgery). Clopidogrel is also used to prevent serious or life-threatening problems with the heart and blood vessels in people who have peripheral arterial disease (poor circulation in the blood vessels that supply blood to the legs). Clopidogrel is in a class of medications called antiplatelet medications. It works by preventing platelets (a type of blood cell) from collecting and forming clots that may cause a heart attack or stroke.

Clopidogrel comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take clopidogrel at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take clopidogrel exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Clopidogrel will help prevent serious problems with your heart and blood vessels only as long as you take the medication. Continue to take clopidogrel even if you feel well. Do not stop taking clopidogrel without talking to your doctor. If you stop taking clopidogrel, there is a higher risk that you may have a heart attack or stroke. If you have a stent, there is also a higher risk that you could develop a blood clot in the stent if you stop taking clopidogrel too soon.

Clopidogrel is also sometimes used to prevent blood clots in people with atrial fibrillation (a condition in which the heart beats irregularly). Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking clopidogrel,

  • tell your doctor and pharmacist if you are allergic to clopidogrel, prasugrel (Effient), ticlopidine, any other medications, or any ingredient in clopidogrel tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn); cilostazol; esomeprazole (Nexium); etravirine (Intelence); omeprazole (Prilosec, Prilosec OTC, Zegerid); certain opiate medications for cough such as codeine (in Triacin-C, in Tuzistra XR, others) or hydrocodone (Hycodan, Tussicaps) or for pain such as codeine (in Fioricet, in Trezix), fentanyl (Actiq, Duragesic, Subsys, others), hydrocodone (Hysingla, Zohydro, in Anexsia, in Norco), meperidine (Demerol), morphine (Duramorph, Kadian), or oxycodone (in Percocet, in Roxicet, others); repaglinide (Prandin, in Prandimet); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft); and selective serotonin/norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), sibutramine (no longer available in the U.S.; Meridia), and venlafaxine (Effexor). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have bleeding ulcers (sores in the lining of the stomach or small intestine that are bleeding), bleeding in the brain, or any other condition that causes severe bleeding. Your doctor may tell you that you should not take clopidogrel.

  • tell your doctor if you have recently been injured and if you have or have ever had liver or kidney disease or any condition that may cause bleeding, including stomach problems such as ulcers.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking clopidogrel, call your doctor.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking clopidogrel. Your doctor may tell you to stop taking clopidogrel at least 5 days prior to your surgery to avoid excessive bleeding during surgery. Your doctor will tell you when to start taking clopidogrel again after your surgery.

  • you should know that you may bleed more easily or for a longer time than usual while you are taking clopidogrel. Be careful not to cut or hurt yourself while you are taking clopidogrel.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • excessive tiredness

    • headache

    • dizziness

    • nausea

    • vomiting

    • stomach pain

    • diarrhea

    • nosebleed

  • Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

    • hives

    • rash

    • itching

    • difficulty breathing or swallowing

    • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

    • hoarseness

    • black and tarry stools

    • red blood in stools

    • bloody vomit

    • vomit that looks like coffee grounds

    • unusual bleeding or bruising

    • pink or brown urine

    • slow or difficult speech

    • weakness or numbness of an arm or a leg

    • changes in vision

    • fever

    • shortness of breath

    • fast heartbeat

    • pale skin

    • purple patches or bleeding under the skin

    • confusion

    • yellowing of the skin or eyes

    • seizures

  • Clopidogrel may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • unusual bruising or bleeding

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The metabolism of Clopidogrel can be decreased when combined with Moxifloxacin.
Repaglinide Repaglinide The risk or severity of hypoglycemia can be increased when Clopidogrel is combined with Repaglinide.
Montelukast Montelukast The metabolism of Montelukast can be decreased when combined with Clopidogrel.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The metabolism of Clopidogrel can be increased when combined with Insulin glargine.
Leflunomide Leflunomide The serum concentration of Clopidogrel can be decreased when it is combined with Leflunomide.
Delavirdine Delavirdine The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Delavirdine resulting in a loss in efficacy.
Nevirapine Nevirapine The metabolism of Clopidogrel can be increased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Clopidogrel can be decreased when combined with Atorvastatin.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Clopidogrel.
Anagrelide Anagrelide Anagrelide may increase the antiplatelet activities of Clopidogrel.
Candesartan Candesartan The metabolism of Candesartan can be decreased when combined with Clopidogrel.
Cilostazol Cilostazol Clopidogrel may increase the antiplatelet activities of Cilostazol.
Diphenoxylate Diphenoxylate Diphenoxylate can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Clopidogrel can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Clopidogrel can be decreased when combined with Conjugated estrogens.
Fenofibrate Fenofibrate The metabolism of Clopidogrel can be decreased when combined with Fenofibrate.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Clopidogrel is combined with Guanfacine.
Olsalazine Olsalazine The risk or severity of bleeding can be increased when Olsalazine is combined with Clopidogrel.
Paregoric Paregoric The serum concentration of the active metabolites of Clopidogrel can be decreased when Clopidogrel is used in combination with Morphine.
Pentazocine Pentazocine Pentazocine can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ranitidine Ranitidine The serum concentration of Ranitidine can be increased when it is combined with Clopidogrel.
Reserpine Reserpine The serum concentration of Reserpine can be increased when it is combined with Clopidogrel.
Tacrolimus Tacrolimus The metabolism of Tacrolimus can be decreased when combined with Clopidogrel.
Tizanidine Tizanidine The metabolism of Clopidogrel can be decreased when combined with Tizanidine.
Triamcinolone Triamcinolone The metabolism of Clopidogrel can be increased when combined with Triamcinolone.
Zolmitriptan Zolmitriptan The metabolism of Clopidogrel can be decreased when combined with Zolmitriptan.
Famotidine Injection Famotidine Injection The metabolism of Clopidogrel can be decreased when combined with Famotidine.
Fluconazole Injection Fluconazole Injection The metabolism of Clopidogrel can be decreased when combined with Fluconazole.
Hydromorphone Injection Hydromorphone Injection Hydromorphone can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Interferon Beta-1b Injection Interferon Beta-1b Injection The metabolism of Clopidogrel can be decreased when combined with Interferon beta-1b.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The metabolism of Clopidogrel can be decreased when combined with Interferon gamma-1b.
Levofloxacin Injection Levofloxacin Injection The metabolism of Clopidogrel can be decreased when combined with Levofloxacin.
Meperidine Injection Meperidine Injection Meperidine can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Metoclopramide Injection Metoclopramide Injection The metabolism of Metoclopramide can be decreased when combined with Clopidogrel.
Metronidazole Injection Metronidazole Injection The metabolism of Clopidogrel can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The serum concentration of the active metabolites of Clopidogrel can be decreased when Clopidogrel is used in combination with Morphine.
Zidovudine Injection Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Clopidogrel.
Altretamine Altretamine The risk or severity of bleeding and hemorrhage can be increased when Amphetamine is combined with Clopidogrel.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Clopidogrel.
Ondansetron Ondansetron The metabolism of Clopidogrel can be decreased when combined with Ondansetron.
Enoxaparin Injection Enoxaparin Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Enoxaparin.
Torsemide Torsemide The metabolism of Torasemide can be decreased when combined with Clopidogrel.
Olanzapine Olanzapine The metabolism of Clopidogrel can be decreased when combined with Olanzapine.
Alosetron Alosetron The metabolism of Clopidogrel can be decreased when combined with Alosetron.
Dofetilide Dofetilide The serum concentration of Dofetilide can be increased when it is combined with Clopidogrel.
Hydroxychloroquine Hydroxychloroquine The metabolism of Hydroxychloroquine can be decreased when combined with Clopidogrel.
Meloxicam Meloxicam The risk or severity of bleeding can be increased when Meloxicam is combined with Clopidogrel.
Oxcarbazepine Oxcarbazepine The metabolism of Clopidogrel can be increased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Pantoprazole resulting in a loss in efficacy.
Telmisartan Telmisartan The metabolism of Clopidogrel can be decreased when combined with Telmisartan.
Temozolomide Temozolomide The risk or severity of bleeding can be increased when Clopidogrel is combined with Temozolomide.
Zaleplon Zaleplon The metabolism of Zaleplon can be decreased when combined with Clopidogrel.
Anakinra Anakinra The metabolism of Clopidogrel can be increased when combined with Anakinra.
Linezolid Linezolid The risk or severity of bleeding and hemorrhage can be increased when Linezolid is combined with Clopidogrel.
Pentosan Polysulfate Pentosan Polysulfate The risk or severity of adverse effects can be increased when Pentosan polysulfate is combined with Clopidogrel.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Clopidogrel.
Etanercept Injection Etanercept Injection The metabolism of Clopidogrel can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Clopidogrel can be decreased when combined with Modafinil.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of bleeding can be increased when Choline magnesium trisalicylate is combined with Clopidogrel.
Sirolimus Sirolimus The metabolism of Sirolimus can be decreased when combined with Clopidogrel.
Dutasteride Dutasteride The metabolism of Dutasteride can be decreased when combined with Clopidogrel.
Epinephrine Injection Epinephrine Injection The serum concentration of Epinephrine can be increased when it is combined with Clopidogrel.
Epirubicin Epirubicin The risk or severity of bleeding can be increased when Clopidogrel is combined with Epirubicin.
Eplerenone Eplerenone The metabolism of Clopidogrel can be decreased when combined with Eplerenone.
Escitalopram Escitalopram The risk or severity of bleeding can be increased when Escitalopram is combined with Clopidogrel.
Zonisamide Zonisamide The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Clopidogrel can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Clopidogrel.
Atazanavir Atazanavir The metabolism of Atazanavir can be decreased when combined with Clopidogrel.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Clopidogrel.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Clopidogrel.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Clopidogrel.
Vardenafil Vardenafil The metabolism of Vardenafil can be decreased when combined with Clopidogrel.
Aprepitant Aprepitant The metabolism of Clopidogrel can be decreased when combined with Aprepitant.
Interferon Beta-1a Subcutaneous Injection Interferon Beta-1a Subcutaneous Injection The metabolism of Clopidogrel can be decreased when combined with Interferon beta-1a.
Memantine Memantine The metabolism of Memantine can be decreased when combined with Clopidogrel.
Tegaserod Tegaserod The metabolism of Clopidogrel can be decreased when combined with Tegaserod.
Tadalafil Tadalafil The metabolism of Tadalafil can be decreased when combined with Clopidogrel.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be decreased when combined with Clopidogrel.
Gemifloxacin Gemifloxacin The metabolism of Clopidogrel can be decreased when combined with Gemifloxacin.
Progesterone Progesterone The metabolism of Clopidogrel can be decreased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Clopidogrel.
Infliximab Injection Infliximab Injection The metabolism of Clopidogrel can be increased when combined with Infliximab.
Oxandrolone Oxandrolone The metabolism of Clopidogrel can be decreased when combined with Oxandrolone.
Rifaximin Rifaximin The therapeutic efficacy of Clopidogrel can be increased when used in combination with Rifaximin.
Duloxetine Duloxetine The risk or severity of hemorrhage can be increased when Duloxetine is combined with Clopidogrel.
Norethindrone Norethindrone The metabolism of Clopidogrel can be decreased when combined with Norethisterone.
Bosentan Bosentan The metabolism of Clopidogrel can be increased when combined with Bosentan.
Cinacalcet Cinacalcet The metabolism of Cinacalcet can be decreased when combined with Clopidogrel.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Clopidogrel.
Eszopiclone Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Clopidogrel.
Ganciclovir Ganciclovir The risk or severity of adverse effects can be increased when Clopidogrel is combined with Ganciclovir.
Voriconazole Voriconazole The metabolism of Clopidogrel can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine The risk or severity of bleeding and hemorrhage can be increased when Amphetamine is combined with Clopidogrel.
Entecavir Entecavir The metabolism of Clopidogrel can be decreased when combined with Entecavir.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The metabolism of Clopidogrel can be decreased when combined with Peginterferon alfa-2a.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The serum concentration of Clopidogrel can be increased when it is combined with Peginterferon alfa-2b.
Isocarboxazid Isocarboxazid The risk or severity of bleeding and hemorrhage can be increased when Isocarboxazid is combined with Clopidogrel.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Clopidogrel.
Fentanyl Fentanyl Fentanyl can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Deferasirox Deferasirox The serum concentration of Clopidogrel can be increased when it is combined with Deferasirox.
Phenylephrine Phenylephrine The metabolism of Clopidogrel can be increased when combined with Phenylephrine.
Tipranavir Tipranavir Tipranavir may increase the antiplatelet activities of Clopidogrel.
Felbamate Felbamate The metabolism of Clopidogrel can be decreased when combined with Felbamate.
Abatacept Injection Abatacept Injection The metabolism of Clopidogrel can be increased when combined with Abatacept.
Rasagiline Rasagiline The risk or severity of bleeding and hemorrhage can be increased when Rasagiline is combined with Clopidogrel.
Imatinib Imatinib The metabolism of Imatinib can be decreased when combined with Clopidogrel.
Sitagliptin Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Clopidogrel.
Varenicline Varenicline The excretion of Varenicline can be decreased when combined with Clopidogrel.
Gefitinib Gefitinib The metabolism of Clopidogrel can be decreased when combined with Gefitinib.
Paliperidone Paliperidone The metabolism of Paliperidone can be decreased when combined with Clopidogrel.
Bortezomib Bortezomib The metabolism of Clopidogrel can be decreased when combined with Bortezomib.
Clofarabine Injection Clofarabine Injection The serum concentration of Clofarabine can be increased when it is combined with Clopidogrel.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The metabolism of Clopidogrel can be increased when combined with Insulin glulisine.
Oxaliplatin Injection Oxaliplatin Injection The serum concentration of Oxaliplatin can be increased when it is combined with Clopidogrel.
Primaquine Primaquine The metabolism of Clopidogrel can be increased when combined with Primaquine.
Rituximab Injection Rituximab Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Rituximab.
Bismuth Subsalicylate Bismuth Subsalicylate The risk or severity of bleeding can be increased when Clopidogrel is combined with Bismuth subsalicylate.
Pemetrexed Injection Pemetrexed Injection The metabolism of Clopidogrel can be decreased when combined with Pemetrexed.
Nabilone Nabilone The metabolism of Clopidogrel can be decreased when combined with Nabilone.
Vorinostat Vorinostat The risk or severity of bleeding can be increased when Clopidogrel is combined with Vorinostat.
Sorafenib Sorafenib The metabolism of Clopidogrel can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Sunitinib can be decreased when combined with Clopidogrel.
Dronabinol Dronabinol The metabolism of Dronabinol can be decreased when combined with Clopidogrel.
Lapatinib Lapatinib The metabolism of Lapatinib can be decreased when combined with Clopidogrel.
Dasatinib Dasatinib Dasatinib may increase the anticoagulant activities of Clopidogrel.
Mexiletine Mexiletine The metabolism of Clopidogrel can be decreased when combined with Mexiletine.
Omega-3 Fatty Acids Omega-3 Fatty Acids Omega-3 fatty acids may increase the antiplatelet activities of Clopidogrel.
Armodafinil Armodafinil The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Armodafinil resulting in a loss in efficacy.
Azacitidine Injection Azacitidine Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Azacitidine.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Clopidogrel.
Nelarabine Injection Nelarabine Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Nelarabine.
Lenalidomide Lenalidomide The risk or severity of bleeding can be increased when Clopidogrel is combined with Lenalidomide.
Nilotinib Nilotinib The metabolism of Clopidogrel can be decreased when combined with Nilotinib.
Bexarotene Bexarotene The metabolism of Bexarotene can be decreased when combined with Clopidogrel.
Budesonide Budesonide The metabolism of Clopidogrel can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Chloramphenicol resulting in a loss in efficacy.
Decitabine Injection Decitabine Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Decitabine.
Etravirine Etravirine The metabolism of Clopidogrel can be decreased when combined with Etravirine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Arsenic trioxide.
Mitoxantrone Injection Mitoxantrone Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Mitoxantrone.
Desvenlafaxine Desvenlafaxine The risk or severity of hemorrhage can be increased when Desvenlafaxine is combined with Clopidogrel.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Clopidogrel.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Clopidogrel.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Clopidogrel.
Flecainide Flecainide The metabolism of Clopidogrel can be decreased when combined with Flecainide.
Certolizumab Injection Certolizumab Injection The metabolism of Clopidogrel can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Ixabepilone.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Clopidogrel.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Clopidogrel.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of bleeding can be increased when Clopidogrel is combined with Alemtuzumab.
Midazolam Midazolam The metabolism of Clopidogrel can be decreased when combined with Midazolam.
Naltrexone Injection Naltrexone Injection Naltrexone can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Dexrazoxane.
Eltrombopag Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Clopidogrel.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Clopidogrel is combined with Ibritumomab tiuxetan.
Milnacipran Milnacipran The risk or severity of hemorrhage can be increased when Milnacipran is combined with Clopidogrel.
Dexlansoprazole Dexlansoprazole The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Dexlansoprazole resulting in a loss in efficacy.
Betaxolol Betaxolol The metabolism of Clopidogrel can be decreased when combined with Betaxolol.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Clopidogrel.
Prasugrel Prasugrel The risk or severity of bleeding can be increased when Clopidogrel is combined with Prasugrel.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Clopidogrel.
Everolimus Everolimus The risk or severity of bleeding can be increased when Clopidogrel is combined with Everolimus.
Dronedarone Dronedarone The metabolism of Clopidogrel can be decreased when combined with Dronedarone.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Clopidogrel.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Clopidogrel.
Tapentadol Tapentadol Tapentadol can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Topotecan Topotecan The risk or severity of bleeding can be increased when Clopidogrel is combined with Topotecan.
Golimumab Injection Golimumab Injection The metabolism of Clopidogrel can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Pazopanib can be decreased when combined with Clopidogrel.
Asenapine Asenapine The metabolism of Asenapine can be decreased when combined with Clopidogrel.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Clopidogrel.
Albendazole Albendazole The metabolism of Clopidogrel can be decreased when combined with Albendazole.
Levonorgestrel Levonorgestrel The metabolism of Clopidogrel can be decreased when combined with Levonorgestrel.
Oxymorphone Oxymorphone Oxymorphone can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Dabigatran Dabigatran The risk or severity of bleeding can be increased when Clopidogrel is combined with Dabigatran.
Tocilizumab Injection Tocilizumab Injection The metabolism of Clopidogrel can be increased when combined with Tocilizumab.
Dalfampridine Dalfampridine The serum concentration of Dalfampridine can be increased when it is combined with Clopidogrel.
Eribulin Injection Eribulin Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Eribulin.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Clopidogrel.
Acetaminophen Injection Acetaminophen Injection The metabolism of Clopidogrel can be decreased when combined with Acetaminophen.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Clopidogrel.
Denileukin Diftitox Injection Denileukin Diftitox Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Aldesleukin.
Busulfan Injection Busulfan Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Busulfan.
Linagliptin Linagliptin The serum concentration of Linagliptin can be increased when it is combined with Clopidogrel.
Rilpivirine Rilpivirine The metabolism of Rilpivirine can be decreased when combined with Clopidogrel.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Clopidogrel.
Abiraterone Abiraterone The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Abiraterone resulting in a loss in efficacy.
Rivaroxaban Rivaroxaban Clopidogrel may increase the anticoagulant activities of Rivaroxaban.
Ticagrelor Ticagrelor The risk or severity of bleeding can be increased when Clopidogrel is combined with Ticagrelor.
Ruxolitinib Ruxolitinib The risk or severity of bleeding can be increased when Clopidogrel is combined with Ruxolitinib.
Clobazam Clobazam The metabolism of Clobazam can be decreased when combined with Clopidogrel.
Vemurafenib Vemurafenib The serum concentration of Clopidogrel can be increased when it is combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Clopidogrel can be decreased when combined with Vismodegib.
Ivacaftor Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Clopidogrel.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Clopidogrel.
Crizotinib Crizotinib The metabolism of Clopidogrel can be decreased when combined with Crizotinib.
Melphalan Injection Melphalan Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Melphalan.
Ambrisentan Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Clopidogrel.
Fondaparinux Injection Fondaparinux Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Fondaparinux.
Carfilzomib Injection Carfilzomib Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Carfilzomib.
Iloprost Iloprost The risk or severity of bleeding can be increased when Clopidogrel is combined with Iloprost.
Enzalutamide Enzalutamide The serum concentration of Enzalutamide can be increased when it is combined with Clopidogrel.
Regorafenib Regorafenib The metabolism of Clopidogrel can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The risk or severity of bleeding can be increased when Clopidogrel is combined with Bosutinib.
Teriflunomide Teriflunomide The serum concentration of Clopidogrel can be decreased when it is combined with Teriflunomide.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Clopidogrel.
Icosapent Ethyl Icosapent Ethyl Clopidogrel may increase the antiplatelet activities of Icosapent ethyl.
Tofacitinib Tofacitinib The risk or severity of bleeding can be increased when Clopidogrel is combined with Tofacitinib.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Clopidogrel.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Clopidogrel.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Clopidogrel.
Apixaban Apixaban The risk or severity of adverse effects can be increased when Clopidogrel is combined with Apixaban.
Dabrafenib Dabrafenib The serum concentration of Clopidogrel can be decreased when it is combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Clopidogrel.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Clopidogrel.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Clopidogrel.
Perampanel Perampanel The metabolism of Perampanel can be decreased when combined with Clopidogrel.
Ibrutinib Ibrutinib The risk or severity of adverse effects can be increased when Ibrutinib is combined with Clopidogrel.
Ketorolac Injection Ketorolac Injection The risk or severity of bleeding can be increased when Ketorolac is combined with Clopidogrel.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Clopidogrel is combined with Obinutuzumab.
Simeprevir Simeprevir The metabolism of Clopidogrel can be decreased when combined with Simeprevir.
Dapagliflozin Dapagliflozin The metabolism of Clopidogrel can be decreased when combined with Dapagliflozin.
Apremilast Apremilast The metabolism of Clopidogrel can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Clopidogrel can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Clopidogrel can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The metabolism of Clopidogrel can be decreased when combined with Eslicarbazepine.
Belinostat Injection Belinostat Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Belinostat.
Testosterone Injection Testosterone Injection The metabolism of Testosterone can be decreased when combined with Clopidogrel.
Oritavancin Injection Oritavancin Injection The metabolism of Clopidogrel can be decreased when combined with Oritavancin.
Vorapaxar Vorapaxar The risk or severity of bleeding can be increased when Clopidogrel is combined with Vorapaxar.
Hydrocodone Hydrocodone Hydrocodone can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Edoxaban Edoxaban The risk or severity of bleeding can be increased when Clopidogrel is combined with Edoxaban.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The metabolism of Clopidogrel can be decreased when combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Olaparib can be decreased when combined with Clopidogrel.
Blinatumomab Injection Blinatumomab Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Blinatumomab.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Clopidogrel.
Riociguat Riociguat The metabolism of Riociguat can be decreased when combined with Clopidogrel.
Pirfenidone Pirfenidone The metabolism of Pirfenidone can be decreased when combined with Clopidogrel.
Secukinumab Injection Secukinumab Injection The metabolism of Clopidogrel can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Clopidogrel can be decreased when combined with Risperidone.
Palbociclib Palbociclib The risk or severity of bleeding can be increased when Clopidogrel is combined with Palbociclib.
Insulin Human Inhalation Insulin Human Inhalation The metabolism of Clopidogrel can be increased when combined with Insulin human.
Lenvatinib Lenvatinib The metabolism of Clopidogrel can be decreased when combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Clopidogrel can be decreased when combined with Naloxegol.
Dinutuximab Injection Dinutuximab Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Clopidogrel.
Deoxycholic Acid Injection Deoxycholic Acid Injection The risk or severity of adverse effects can be increased when Clopidogrel is combined with Deoxycholic acid.
Daclatasvir Daclatasvir The metabolism of Daclatasvir can be decreased when combined with Clopidogrel.
Ziprasidone Injection Ziprasidone Injection The metabolism of Clopidogrel can be decreased when combined with Ziprasidone.
Eluxadoline Eluxadoline Eluxadoline can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The metabolism of Clopidogrel can be increased when combined with Insulin degludec.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Clopidogrel.
Osimertinib Osimertinib The serum concentration of Clopidogrel can be decreased when it is combined with Osimertinib.
Rifapentine Rifapentine The therapeutic efficacy of Clopidogrel can be increased when used in combination with Rifapentine.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Clopidogrel.
Dexamethasone Injection Dexamethasone Injection The metabolism of Clopidogrel can be increased when combined with Dexamethasone.
Defibrotide Injection Defibrotide Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Defibrotide.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Clopidogrel.
Cobicistat Cobicistat The metabolism of Clopidogrel can be decreased when combined with Cobicistat.
Selexipag Selexipag The metabolism of Selexipag can be decreased when combined with Clopidogrel.
Obeticholic Acid Obeticholic Acid The risk or severity of adverse effects can be increased when Clopidogrel is combined with Obeticholic acid.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Clopidogrel.
Rucaparib Rucaparib The metabolism of Clopidogrel can be decreased when combined with Rucaparib.
Brigatinib Brigatinib The metabolism of Brigatinib can be decreased when combined with Clopidogrel.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Clopidogrel.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Clopidogrel.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Clopidogrel.
Deflazacort Deflazacort The metabolism of Clopidogrel can be increased when combined with Deflazacort.
Safinamide Safinamide The risk or severity of bleeding and hemorrhage can be increased when Safinamide is combined with Clopidogrel.
Midostaurin Midostaurin The metabolism of Clopidogrel can be decreased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Enasidenib can be decreased when combined with Clopidogrel.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Clopidogrel.
Delafloxacin Delafloxacin The metabolism of Clopidogrel can be increased when combined with Delafloxacin.
Betrixaban Betrixaban The risk or severity of bleeding can be increased when Clopidogrel is combined with Betrixaban.
Acalabrutinib Acalabrutinib The metabolism of Clopidogrel can be decreased when combined with Acalabrutinib.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Gemtuzumab ozogamicin.
Letermovir Letermovir The metabolism of Clopidogrel can be decreased when combined with Letermovir.
Buprenorphine Injection Buprenorphine Injection Buprenorphine can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Apalutamide Apalutamide The serum concentration of Apalutamide can be increased when it is combined with Clopidogrel.
Penicillamine Penicillamine The risk or severity of bleeding can be increased when Clopidogrel is combined with Penicillamine.
Avatrombopag Avatrombopag The metabolism of Clopidogrel can be increased when combined with Avatrombopag.
Lofexidine Lofexidine The metabolism of Lofexidine can be decreased when combined with Clopidogrel.
Binimetinib Binimetinib The metabolism of Binimetinib can be decreased when combined with Clopidogrel.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Clopidogrel.
Doravirine Doravirine The metabolism of Doravirine can be decreased when combined with Clopidogrel.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Clopidogrel.
Dacomitinib Dacomitinib The metabolism of Dacomitinib can be decreased when combined with Clopidogrel.
Stiripentol Stiripentol The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Stiripentol resulting in a loss in efficacy.
Glasdegib Glasdegib The metabolism of Glasdegib can be decreased when combined with Clopidogrel.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Clopidogrel.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Clopidogrel.
Rifamycin Rifamycin The therapeutic efficacy of Clopidogrel can be increased when used in combination with Rifamycin.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Clopidogrel can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be decreased when combined with Clopidogrel.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Clopidogrel.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection Clopidogrel may increase the antiplatelet activities of Caplacizumab.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Clopidogrel.
Esomeprazole Injection Esomeprazole Injection The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Esomeprazole resulting in a loss in efficacy.
Alpelisib Alpelisib The serum concentration of Clopidogrel can be decreased when it is combined with Alpelisib.
Cladribine Cladribine The risk or severity of bleeding can be increased when Clopidogrel is combined with Cladribine.
Solriamfetol Solriamfetol The serum concentration of Solriamfetol can be increased when it is combined with Clopidogrel.
Triclabendazole Triclabendazole The metabolism of Clopidogrel can be decreased when combined with Triclabendazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Clopidogrel.
Pitolisant Pitolisant The serum concentration of Clopidogrel can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Fedratinib can be decreased when combined with Clopidogrel.
Phenytoin Injection Phenytoin Injection The metabolism of Clopidogrel can be decreased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Clopidogrel.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Clopidogrel.
Voxelotor Voxelotor The metabolism of Voxelotor can be decreased when combined with Clopidogrel.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Clopidogrel.
Cenobamate Cenobamate The serum concentration of Clopidogrel can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod The metabolism of Ozanimod can be decreased when combined with Clopidogrel.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Clopidogrel.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Clopidogrel.
Capmatinib Capmatinib The metabolism of Clopidogrel can be decreased when combined with Capmatinib.
Lemborexant Lemborexant The serum concentration of Clopidogrel can be decreased when it is combined with Lemborexant.
Pralsetinib Pralsetinib The metabolism of Clopidogrel can be decreased when combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Clopidogrel can be decreased when it is combined with Satralizumab.
Viloxazine Viloxazine The metabolism of Clopidogrel can be decreased when combined with Viloxazine.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) Vitamin E may increase the antiplatelet activities of Clopidogrel.
Theophylline Theophylline The metabolism of Theophylline can be decreased when combined with Clopidogrel.
Fenoprofen Fenoprofen The risk or severity of bleeding can be increased when Fenoprofen is combined with Clopidogrel.
Indomethacin Indomethacin The risk or severity of bleeding can be increased when Indomethacin is combined with Clopidogrel.
Mefenamic Acid Mefenamic Acid The risk or severity of bleeding can be increased when Mefenamic acid is combined with Clopidogrel.
Naproxen Naproxen The risk or severity of bleeding can be increased when Naproxen is combined with Clopidogrel.
Tolmetin Tolmetin The risk or severity of bleeding can be increased when Tolmetin is combined with Clopidogrel.
Sulindac Sulindac The risk or severity of bleeding can be increased when Sulindac is combined with Clopidogrel.
Trazodone Trazodone The risk or severity of bleeding can be increased when Trazodone is combined with Clopidogrel.
Hydroxyurea Hydroxyurea The risk or severity of bleeding can be increased when Clopidogrel is combined with Hydroxyurea.
Floxuridine Floxuridine The metabolism of Clopidogrel can be decreased when combined with Floxuridine.
Phenobarbital Phenobarbital The metabolism of Clopidogrel can be decreased when combined with Phenobarbital.
Methotrexate Injection Methotrexate Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Methotrexate.
Levorphanol Levorphanol Levorphanol can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Primidone Primidone The metabolism of Primidone can be increased when combined with Clopidogrel.
Methsuximide Methsuximide The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Methsuximide.
Chlorpromazine Chlorpromazine The metabolism of Clopidogrel can be decreased when combined with Chlorpromazine.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Clopidogrel.
Carmustine Carmustine The metabolism of Clopidogrel can be decreased when combined with Carmustine.
Amantadine Amantadine The serum concentration of Amantadine can be increased when it is combined with Clopidogrel.
Codeine Codeine Codeine can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Tranylcypromine Tranylcypromine The risk or severity of bleeding and hemorrhage can be increased when Tranylcypromine is combined with Clopidogrel.
Phenelzine Phenelzine The risk or severity of bleeding and hemorrhage can be increased when Phenelzine is combined with Clopidogrel.
Procarbazine Procarbazine The risk or severity of bleeding and hemorrhage can be increased when Procarbazine is combined with Clopidogrel.
Thioguanine Thioguanine The risk or severity of bleeding can be increased when Clopidogrel is combined with Tioguanine.
Thioridazine Thioridazine The metabolism of Clopidogrel can be decreased when combined with Thioridazine.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be decreased when combined with Clopidogrel.
Dapsone Dapsone The metabolism of Dapsone can be decreased when combined with Clopidogrel.
Sulfadiazine Sulfadiazine The metabolism of Sulfadiazine can be decreased when combined with Clopidogrel.
Oxycodone Oxycodone Oxycodone can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Methadone Methadone Methadone can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Clopidogrel.
Maprotiline Maprotiline The metabolism of Maprotiline can be decreased when combined with Clopidogrel.
Ibuprofen Ibuprofen The risk or severity of bleeding can be increased when Ibuprofen is combined with Clopidogrel.
Orphenadrine Orphenadrine The metabolism of Clopidogrel can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Perphenazine can be decreased when combined with Clopidogrel.
Azathioprine Azathioprine The metabolism of Azathioprine can be decreased when combined with Clopidogrel.
Sulfasalazine Sulfasalazine The risk or severity of bleeding can be increased when Sulfasalazine is combined with Clopidogrel.
Hydrocortisone Hydrocortisone The metabolism of Clopidogrel can be increased when combined with Hydrocortisone.
Lomustine Lomustine The risk or severity of bleeding can be increased when Clopidogrel is combined with Lomustine.
Doxorubicin Doxorubicin The metabolism of Clopidogrel can be decreased when combined with Doxorubicin.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Clopidogrel is combined with Cytarabine.
Mechlorethamine Mechlorethamine The risk or severity of bleeding can be increased when Clopidogrel is combined with Mechlorethamine.
Dactinomycin Dactinomycin The risk or severity of bleeding can be increased when Clopidogrel is combined with Dactinomycin.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Clopidogrel.
Clonidine Clonidine The metabolism of Clopidogrel can be decreased when combined with Clonidine.
Prazosin Prazosin The serum concentration of Prazosin can be increased when it is combined with Clopidogrel.
Cimetidine Cimetidine The serum concentration of Cimetidine can be increased when it is combined with Clopidogrel.
Warfarin Warfarin The risk or severity of bleeding can be increased when Clopidogrel is combined with Warfarin.
Loperamide Loperamide The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Loperamide.
Promethazine Promethazine The metabolism of Clopidogrel can be decreased when combined with Promethazine.
Meclofenamate Meclofenamate The risk or severity of bleeding can be increased when Meclofenamic acid is combined with Clopidogrel.
Daunorubicin Daunorubicin The metabolism of Clopidogrel can be increased when combined with Daunorubicin.
Griseofulvin Griseofulvin The metabolism of Clopidogrel can be increased when combined with Griseofulvin.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Clopidogrel.
Quinine Quinine The metabolism of Quinine can be decreased when combined with Clopidogrel.
Ethosuximide Ethosuximide The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Ethosuximide.
Triamterene Triamterene The metabolism of Clopidogrel can be decreased when combined with Triamterene.
Sulfinpyrazone Sulfinpyrazone The metabolism of Clopidogrel can be decreased when combined with Sulfinpyrazone.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Clopidogrel.
Secobarbital Secobarbital The metabolism of Clopidogrel can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Clopidogrel.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Clopidogrel.
Imipramine Imipramine The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Imipramine resulting in a loss in efficacy.
Probenecid Probenecid The metabolism of Clopidogrel can be decreased when combined with Probenecid.
Quinidine Quinidine The metabolism of Clopidogrel can be decreased when combined with Quinidine.
Procainamide Procainamide The serum concentration of Procainamide can be increased when it is combined with Clopidogrel.
Isoniazid Isoniazid The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Isoniazid resulting in a loss in efficacy.
Rifampin Rifampin The therapeutic efficacy of Clopidogrel can be increased when used in combination with Rifampicin.
Disopyramide Disopyramide The metabolism of Clopidogrel can be decreased when combined with Disopyramide.
Valproic Acid Valproic Acid The metabolism of Clopidogrel can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Clopidogrel can be decreased when combined with Tamoxifen.
Mitomycin Mitomycin The risk or severity of bleeding can be increased when Clopidogrel is combined with Mitomycin.
Methimazole Methimazole The metabolism of Clopidogrel can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil The risk or severity of bleeding can be increased when Clopidogrel is combined with Propylthiouracil.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Clopidogrel.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Clopidogrel.
Tolazamide Tolazamide The metabolism of Tolazamide can be decreased when combined with Clopidogrel.
Dextromethorphan Dextromethorphan The metabolism of Clopidogrel can be decreased when combined with Dextromethorphan.
Cyclobenzaprine Cyclobenzaprine The metabolism of Cyclobenzaprine can be decreased when combined with Clopidogrel.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Clopidogrel.
Brompheniramine Brompheniramine The metabolism of Brompheniramine can be decreased when combined with Clopidogrel.
Chlorzoxazone Chlorzoxazone The metabolism of Clopidogrel can be decreased when combined with Chlorzoxazone.
Carisoprodol Carisoprodol The metabolism of Clopidogrel can be decreased when combined with Carisoprodol.
Disulfiram Disulfiram The metabolism of Disulfiram can be decreased when combined with Clopidogrel.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Clopidogrel can be decreased when combined with Propranolol.
Mercaptopurine Mercaptopurine The risk or severity of bleeding can be increased when Clopidogrel is combined with Mercaptopurine.
Butorphanol Injection Butorphanol Injection Butorphanol can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nalbuphine Injection Nalbuphine Injection Nalbuphine can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Clopidogrel.
Colchicine Colchicine The metabolism of Clopidogrel can be decreased when combined with Colchicine.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Clopidogrel.
Ketoconazole Ketoconazole The metabolism of Clopidogrel can be decreased when combined with Ketoconazole.
Thiotepa Injection Thiotepa Injection The metabolism of Clopidogrel can be decreased when combined with Thiotepa.
Vincristine Injection Vincristine Injection The metabolism of Clopidogrel can be decreased when combined with Vincristine.
Dipyridamole Dipyridamole The risk or severity of bleeding can be increased when Clopidogrel is combined with Dipyridamole.
Vinblastine Vinblastine The risk or severity of bleeding can be increased when Clopidogrel is combined with Vinblastine.
Hydroxyzine Hydroxyzine The metabolism of Clopidogrel can be decreased when combined with Hydroxyzine.
Thiothixene Thiothixene The metabolism of Thiothixene can be decreased when combined with Clopidogrel.
Salsalate Salsalate The risk or severity of bleeding can be increased when Salsalate is combined with Clopidogrel.
Chlorambucil Chlorambucil The risk or severity of bleeding can be increased when Clopidogrel is combined with Chlorambucil.
Alprazolam Alprazolam The metabolism of Clopidogrel can be decreased when combined with Alprazolam.
Triazolam Triazolam The metabolism of Triazolam can be decreased when combined with Clopidogrel.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Clopidogrel.
Diltiazem Diltiazem The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Diltiazem.
Nifedipine Nifedipine The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Nifedipine.
Timolol Timolol The metabolism of Clopidogrel can be decreased when combined with Timolol.
Verapamil Verapamil The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Verapamil.
Cisplatin Injection Cisplatin Injection The serum concentration of Cisplatin can be increased when it is combined with Clopidogrel.
Diflunisal Diflunisal The risk or severity of bleeding can be increased when Diflunisal is combined with Clopidogrel.
Piroxicam Piroxicam The risk or severity of bleeding can be increased when Piroxicam is combined with Clopidogrel.
Streptozocin Streptozocin The metabolism of Clopidogrel can be increased when combined with Streptozocin.
Etoposide Etoposide The metabolism of Etoposide can be decreased when combined with Clopidogrel.
Glyburide Glyburide The metabolism of Glyburide can be decreased when combined with Clopidogrel.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Clopidogrel.
Nafcillin Injection Nafcillin Injection The metabolism of Clopidogrel can be increased when combined with Nafcillin.
Pentoxifylline Pentoxifylline Pentoxifylline may increase the antiplatelet activities of Clopidogrel.
Pentamidine Injection Pentamidine Injection The metabolism of Clopidogrel can be decreased when combined with Pentamidine.
Labetalol Labetalol The metabolism of Clopidogrel can be decreased when combined with Labetalol.
Gemfibrozil Gemfibrozil The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Gemfibrozil resulting in a loss in efficacy.
Guanabenz Guanabenz The metabolism of Clopidogrel can be decreased when combined with Guanabenz.
Ketoprofen Ketoprofen The risk or severity of bleeding can be increased when Ketoprofen is combined with Clopidogrel.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Clopidogrel.
Flurbiprofen Flurbiprofen The risk or severity of bleeding can be increased when Flurbiprofen is combined with Clopidogrel.
Amiodarone Amiodarone The risk or severity of bleeding can be increased when Amiodarone is combined with Clopidogrel.
Buspirone Buspirone The metabolism of Clopidogrel can be decreased when combined with Buspirone.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Clopidogrel.
Ciprofloxacin Ciprofloxacin The metabolism of Clopidogrel can be decreased when combined with Ciprofloxacin.
Mesalamine Mesalamine The risk or severity of bleeding can be increased when Mesalazine is combined with Clopidogrel.
Diclofenac Diclofenac The risk or severity of bleeding can be increased when Diclofenac is combined with Clopidogrel.
Fluoxetine Fluoxetine The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Fluoxetine resulting in a loss in efficacy.
Nimodipine Nimodipine The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Nimodipine.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The metabolism of Clopidogrel can be decreased when combined with Interferon alfa-2b.
Clozapine Clozapine The metabolism of Clozapine can be decreased when combined with Clopidogrel.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Clopidogrel.
Ofloxacin Ofloxacin The metabolism of Clopidogrel can be decreased when combined with Ofloxacin.
Fludarabine Injection Fludarabine Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Fludarabine.
Pentostatin Injection Pentostatin Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Pentostatin.
Clarithromycin Clarithromycin The metabolism of Clopidogrel can be decreased when combined with Clarithromycin.
Etodolac Etodolac The risk or severity of bleeding can be increased when Etodolac is combined with Clopidogrel.
Felodipine Felodipine The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Felodipine.
Nabumetone Nabumetone The risk or severity of bleeding can be increased when Nabumetone is combined with Clopidogrel.
Simvastatin Simvastatin The metabolism of Simvastatin can be decreased when combined with Clopidogrel.
Amlodipine Amlodipine The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Amlodipine.
Teniposide Injection Teniposide Injection The metabolism of Clopidogrel can be decreased when combined with Teniposide.
Itraconazole Itraconazole The metabolism of Clopidogrel can be decreased when combined with Itraconazole.
Oxaprozin Oxaprozin The risk or severity of bleeding can be increased when Oxaprozin is combined with Clopidogrel.
Atovaquone Atovaquone The metabolism of Clopidogrel can be decreased when combined with Atovaquone.
Rifabutin Rifabutin The therapeutic efficacy of Clopidogrel can be increased when used in combination with Rifabutin.
Zolpidem Zolpidem The metabolism of Clopidogrel can be decreased when combined with Zolpidem.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Clopidogrel.
Isradipine Isradipine The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Isradipine.
Omeprazole Omeprazole The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Omeprazole resulting in a loss in efficacy.
Cisapride Cisapride The metabolism of Clopidogrel can be decreased when combined with Cisapride.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Clopidogrel.
Venlafaxine Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Clopidogrel.
Fluvoxamine Fluvoxamine The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Fluvoxamine resulting in a loss in efficacy.
Nefazodone Nefazodone The risk or severity of hemorrhage can be increased when Nefazodone is combined with Clopidogrel.
Lamotrigine Lamotrigine The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Lamotrigine.
Losartan Losartan The metabolism of Losartan can be decreased when combined with Clopidogrel.
Tramadol Tramadol Tramadol can cause a decrease in the absorption of Clopidogrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Vinorelbine Injection Vinorelbine Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Vinorelbine.
Carboplatin Injection Carboplatin Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Carboplatin.
Lansoprazole Lansoprazole The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Lansoprazole resulting in a loss in efficacy.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Clopidogrel.
Nicardipine Nicardipine The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Nicardipine.
Bupropion Bupropion The metabolism of Bupropion can be decreased when combined with Clopidogrel.
Ticlopidine Ticlopidine The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Ticlopidine resulting in a loss in efficacy.
Saquinavir Saquinavir The metabolism of Saquinavir can be decreased when combined with Clopidogrel.
Metformin Metformin The serum concentration of Metformin can be increased when it is combined with Clopidogrel.
Dalteparin Injection Dalteparin Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Dalteparin.
Nisoldipine Nisoldipine The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Nisoldipine.
Lamivudine Lamivudine The serum concentration of Lamivudine can be increased when it is combined with Clopidogrel.
Riluzole Riluzole The metabolism of Clopidogrel can be decreased when combined with Riluzole.
Glimepiride Glimepiride The metabolism of Glimepiride can be decreased when combined with Clopidogrel.
Anastrozole Anastrozole The metabolism of Clopidogrel can be decreased when combined with Anastrozole.
Gemcitabine Injection Gemcitabine Injection The risk or severity of bleeding can be increased when Clopidogrel is combined with Gemcitabine.
Indinavir Indinavir The metabolism of Clopidogrel can be decreased when combined with Indinavir.
Ritonavir Ritonavir The serum concentration of Clopidogrel can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Clopidogrel.
Clomipramine Clomipramine The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Clomipramine resulting in a loss in efficacy.
Zafirlukast Zafirlukast The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Zafirlukast resulting in a loss in efficacy.
Mirtazapine Mirtazapine The metabolism of Clopidogrel can be decreased when combined with Mirtazapine.
Topiramate Topiramate The metabolism of Clopidogrel can be decreased when combined with Topiramate.
Zileuton Zileuton The metabolism of Clopidogrel can be decreased when combined with Zileuton.
Valsartan Valsartan The metabolism of Clopidogrel can be decreased when combined with Valsartan.
Insulin Lispro Injection Insulin Lispro Injection The metabolism of Clopidogrel can be increased when combined with Insulin lispro.
Pramipexole Pramipexole The serum concentration of Pramipexole can be increased when it is combined with Clopidogrel.
Donepezil Donepezil The metabolism of Donepezil can be decreased when combined with Clopidogrel.
Nelfinavir Nelfinavir The metabolism of Clopidogrel can be decreased when combined with Nelfinavir.
Carvedilol Carvedilol The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Carvedilol.
Nilutamide Nilutamide The metabolism of Clopidogrel can be decreased when combined with Nilutamide.
Flutamide Flutamide The metabolism of Clopidogrel can be decreased when combined with Flutamide.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Clopidogrel.
Bicalutamide Bicalutamide The metabolism of Clopidogrel can be decreased when combined with Bicalutamide.
Sertraline Sertraline The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Sertraline resulting in a loss in efficacy.
Propafenone Propafenone The metabolism of Clopidogrel can be decreased when combined with Propafenone.
Letrozole Letrozole The metabolism of Clopidogrel can be decreased when combined with Letrozole.
Raloxifene Raloxifene The metabolism of Clopidogrel can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Clopidogrel.
Finasteride Finasteride The metabolism of Finasteride can be decreased when combined with Clopidogrel.
Quetiapine Quetiapine The metabolism of Quetiapine can be decreased when combined with Clopidogrel.
Paroxetine Paroxetine The metabolism of Clopidogrel can be decreased when combined with Paroxetine.
Tolcapone Tolcapone The metabolism of Clopidogrel can be decreased when combined with Tolcapone.
Citalopram Citalopram The risk or severity of hemorrhage can be increased when Citalopram is combined with Clopidogrel.
Capecitabine Capecitabine The metabolism of Clopidogrel can be decreased when combined with Capecitabine.
Efavirenz Efavirenz The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Efavirenz resulting in a loss in efficacy.
Sildenafil Sildenafil The metabolism of Sildenafil can be decreased when combined with Clopidogrel.
Pioglitazone Pioglitazone The serum concentration of Pioglitazone can be increased when it is combined with Clopidogrel.
Celecoxib Celecoxib The risk or severity of bleeding can be increased when Celecoxib is combined with Clopidogrel.
Rosiglitazone Rosiglitazone The metabolism of Rosiglitazone can be decreased when combined with Clopidogrel.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Clopidogrel.
Thalidomide Thalidomide The metabolism of Clopidogrel can be increased when combined with Thalidomide.
Balsalazide Balsalazide The risk or severity of bleeding can be increased when Balsalazide is combined with Clopidogrel.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Clopidogrel.
Rabeprazole Rabeprazole The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Rabeprazole resulting in a loss in efficacy.
Terbinafine Terbinafine The metabolism of Terbinafine can be decreased when combined with Clopidogrel.

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