Abatacept Injection

44 interactions 71 cited references

Also sold as: Orencia Orencia®

About Abatacept Injection

Abatacept is used: alone or in combination with other medications to reduce the pain, swelling, difficulty with daily activities, and joint damage caused by rheumatoid arthritis (a condition in which the body attacks its own joints causing pain, swelling, and loss of function) in adults who have not been helped by othe… Read the full Abatacept Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Adalimumab Alefacept Anakinra Anifrolumab-Fnia Baricitinib Brodalumab

26 Major 18 Moderate

All (44) Major (26) Moderate (18)

Major

Abatacept Injection Adalimumab An increased risk of infection Details Abatacept Injection Alefacept An increased risk of infection Details Abatacept Injection Anakinra Kineret An increased risk of infection Details Abatacept Injection Anifrolumab-Fnia Saphnelo Additive effects due to duplication of therapy Details Abatacept Injection Baricitinib Olumiant An increased risk of infection Details Abatacept Injection Brodalumab An increased risk of infection Details Abatacept Injection Certolizumab Pegol An increased risk of infection Details Abatacept Injection Etanercept An increased risk of infection Details Abatacept Injection Fedratinib Inrebic An increased risk of infection Details Abatacept Injection Golimumab An increased risk of infection Details Abatacept Injection Guselkumab An increased risk of infection Details Abatacept Injection Infliximab Avsola An increased risk of infection Details Abatacept Injection Ixekizumab An increased risk of infection Details Abatacept Injection Natalizumab An increased risk of infection Details Abatacept Injection Risankizumab An increased risk of infection Details Abatacept Injection Rituximab An increased risk of infection Details Abatacept Injection Ruxolitinib Jakafi An increased risk of infection Details Abatacept Injection Sarilumab An increased risk of infection Details Abatacept Injection Secukinumab An increased risk of infection Details Abatacept Injection Tildrakizumab An increased risk of infection Details Abatacept Injection Tocilizumab Actemra An increased risk of infection Details Abatacept Injection Tofacitinib Xeljanz An increased risk of infection Details Abatacept Injection Upadacitinib Rinvoq An increased risk of infection Details Abatacept Injection Ustekinumab An increased risk of infection Details Abatacept Injection Vedolizumab An increased risk of infection Details Abatacept Injection Glucose Measurement, Blood A falsely elevated blood glucose measurement Details

Moderate

Abatacept Injection Adenovirus Vaccine Type 4, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Injection Adenovirus Vaccine Type 7, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Injection Bacillus Of Calmette And Guerin Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Injection Dengue Tetravalent Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Injection Influenza Virus Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Injection Measles Virus Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Injection Mumps Virus Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Injection Poliovirus Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Injection Rotavirus Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Injection Rubella Virus Vaccine, Live Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Injection Sars-Cov-2 (Covid-19) Vaccine, Adenovirus 26 Vector (Janssen) Decreased immune response to COVID-19 vaccine Details Abatacept Injection Sars-Cov-2 (Covid-19) Vaccine, Mrna (Moderna) Decreased immune response to COVID-19 vaccine Details Abatacept Injection Sars-Cov-2 (Covid-19) Vaccine, Mrna (Pfizer) Decreased immune response to COVID-19 vaccine Details Abatacept Injection Smallpox Monkeypox Vaccine Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.