Drug Interactions Directory

2,618 drugs with documented interactions.

2,618Drugs
67,117Interactions
53,805Serious (major+)
PharmacistReviewed
1Look up a drugSearch by generic or brand name, or browse A-Z.
2Scan the severityInteractions are grouped and color-coded by how much they matter.
3Read the write-upPlain-English and clinical explanations, with cited evidence.
Popular: Buprenorphine 633 Hydroxychloroquine 631 Ketoconazole Topical 546 Cyclosporine Injection 545 Cyclosporine Ophthalmic 545 Sertraline 532 Amitriptyline 525 Fentanyl Transdermal Patch 493

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

A
Abacavir 15 Abametapir 185 Abatacept 51 Abatacept Injection 44 Abciximab 50 Abemaciclib 128 Abiraterone 164 Abiraterone Acetate 41 Abiraterone Acetate, Micronized 41 Abrocitinib 67 Acalabrutinib 153 Acarbose 135 Acebutolol 188 Acecainide 23 Aceclofenac 95 Acemetacin 87 Acenocoumarol 95 Acepromazine 17 Acetaminophen 33 Acetaminophen And Codeine 489 Acetaminophen Injection 28 Acetaminophen Rectal 28 Acetazolamide 46 Acetazolamide Sodium 2 Acetohexamide 8 Acetophenazine 7 Acetylcysteine 6 Acetylcysteine Oral Inhalation 2 Acetyldigoxin 12 Acitretin 25 Aclidinium 12 Aclidinium Oral Inhalation 43 Acoramidis 4 Acrivastine 1 Activated Charcoal 3 Acyclovir 25 Acyclovir Injection 24 Acyclovir Ophthalmic 24 Acyclovir Topical 24 Adagrasib 124 Adalimumab 13 Adalimumab Injection 34 Adenosine 4 Adenovirus Vaccine Type 4, Live 204 Adenovirus Vaccine Type 7, Live 204 Ado-Trastuzumab Emtansine 1 Ado-Trastuzumab Emtansine Injection 35 Afatinib 54 Aficamten 53 Agalsidase Alfa 4 Agomelatine 2 Ajmaline 14 Alacepril 10 Albendazole 13 Albiglutide 42 Albuterol 16 Albuterol Oral Inhalation 86 Albuterol Sulfate 1 Alcaftadine 1 Alcaftadine Ophthalmic 7 Alclofenac 1 Alclometasone 6 Alcuronium 12 Aldesleukin 33 Aldosterone 5 Alectinib 17 Alefacept 8 Alendronate 14 Alfalfa 9 Alfentanil 100 Alfuzosin 297 Alipogene Tiparvovec 15 Aliskiren 51 Alitretinoin 4 Alizapride 1 Allopurinol 32 Allopurinol Injection 26 Almotriptan 22 Aloe 1 Alogliptin 129 Alosetron 8 Alpelisib 87 Alprazolam 44 Alprenolol 4 Alprostadil 2 Alteplase, Recombinant 34 Aluminum 5 Aluminum Carbonate, Basic 56 Aluminum Distearate 1 Aluminum Hydroxide 58 Aluminum Oxide 5 Aluminum Phosphate 56 Alvimopan 5 Amantadine 22 Ambenonium 2 Ambrisentan 11 Amcinonide 6 Amdinocillin 6 Amifampridine 39 Amikacin 19 Amikacin Injection 75 Amikacin Liposome 3 Amikacin Oral Inhalation 75 Amiloride 49 Amineptine 47 Aminocaproic Acid 2 Aminocaproic Acid Injection 2 Aminoglutethimide 4 Aminolevulinic Acid 18 Aminophylline 2 Aminosalicylic Acid 4 Amiodarone 141 Amisulpride 62 Amisulpride Injection 215 Amitriptyline 525 Amitriptylinoxide 46 Amivantamab-Vmjw Injection 15 Amlodipine 195 Ammonium Chloride 1 Amobarbital 31