Brodalumab Injection

36 interactions 44 cited references

Also sold as: Siliq Siliq®

About Brodalumab Injection

Brodalumab injection is used to treat moderate to severe plaque psoriasis (skin disease in which red, scaly patches form on some areas of the body) in people whose psoriasis is too severe to be treated by topical medications alone and who have not been treated successfully with other medications. Brodalumab injection i… Read the full Brodalumab Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abatacept Adenovirus Vaccine Type 4, Live Adenovirus Vaccine Type 7, Live Alfentanil Anifrolumab-Fnia Bacillus Of Calmette And Guerin Vaccine, Live

32 Major 4 Moderate

All (36) Major (32) Moderate (4)

Major

Brodalumab Injection Abatacept Orencia An increased risk of infection Details Brodalumab Injection Adenovirus Vaccine Type 4, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Adenovirus Vaccine Type 7, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Alfentanil Increased ALfentanil exposure and an increased risk of respiratory depression Details Brodalumab Injection Anifrolumab-Fnia Saphnelo Additive effects due to duplication of therapy Details Brodalumab Injection Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Cholera Vaccine, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Dengue Tetravalent Vaccine, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Brodalumab Injection Haloperidol Increased haloperidol exposure and an increased risk of haloperidol-related adverse events, including QTc interval prolongation Details Brodalumab Injection Infliximab Avsola Increased immunosuppression and an increased risk of infections Details Brodalumab Injection Influenza Virus Vaccine, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Lemborexant Dayvigo Increased lemborexant exposure and an increased risk of lemborexant-related adverse reactions. Details Brodalumab Injection Lomitapide Increased lomitapide exposure Details Brodalumab Injection Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Brodalumab Injection Measles Virus Vaccine, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Methylergonovine Methergine Increased methylergonovine exposure Details Brodalumab Injection Mifepristone Korlym Increased miFEPRIStone exposure Details Brodalumab Injection Mumps Virus Vaccine, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Nifedipine Adalat® Increased NIFEdipine exposure Details Brodalumab Injection Pimozide Increased pimozide exposure Details Brodalumab Injection Poliovirus Vaccine, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Roflumilast Daliresp Increased roflumilast exposure and an increased risk of roflumilast-related adverse events Details Brodalumab Injection Rotavirus Vaccine, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Rubella Virus Vaccine, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Smallpox Monkeypox Vaccine An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Tramadol ConZip Increased traMADol exposure and an increased risk of seizures, serotonin syndrome and opioid toxicity Details Brodalumab Injection Typhoid Vaccine, Live Vivotif An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Varicella Virus Vaccine, Live An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Voriconazole Vfend Increased voriconazole exposure and an increased risk of voriconazole-related adverse reaction Details Brodalumab Injection Yellow Fever Vaccine Stamaril An increased risk of infection caused by the live or attenuated vaccine Details Brodalumab Injection Zoster Vaccine, Live An increased risk of infection caused by the live or attenuated vaccine Details

Moderate

Brodalumab Injection Artemether Increased artemether/lumefantrine exposure and an increased risk of potentiated QT prolongation Details Brodalumab Injection Dofetilide Tikosyn Increased dofetilide exposure Details Brodalumab Injection Hydrocortisone Ala-Cort Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Brodalumab Injection Lumefantrine Increased artemether/lumefantrine exposure and an increased risk of potentiated QT prolongation Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.