Dasatinib

342 interactions 1 explained in plain English 511 cited references

Also sold as: Phyrago Sprycel Sprycel®

About Dasatinib

Dasatinib is used to treat a certain type of chronic myeloid leukemia (CML; a type of cancer of the white blood cells) as a first treatment and in adults who can no longer benefit from other leukemia medications including imatinib (Gleevec) or in those who cannot take these medications because of side effects. Dasatini… Read the full Dasatinib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Bacillus Of Calmette And Guerin Vaccine, Live Sparfloxacin Typhoid Vaccine Terfenadine Thioridazine Bepridil

25 Contraindicated 297 Major 20 Moderate

All (342) Contraindicated (25) Major (297) Moderate (20)

Contraindicated

Dasatinib Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Dasatinib Bepridil An increased risk of QT interval prolongation Details Dasatinib Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Dasatinib Dronedarone Multaq Increased risk of QT interval prolongation Details Dasatinib Ensitrelvir Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details Dasatinib Fluconazole Diflucan An increased risk of QT interval prolongation and increased dasatinib exposure Details Dasatinib Lefamulin Xenleta Increased sensitive CYP3A4 substrates exposure and an increased risk of QT interval prolongation Details Dasatinib Levoketoconazole Recorlev An increased risk of QT interval prolongation, an increased CYP3A4 substrate exposure and an increased risk of CYP3A substrate-rel... Details Dasatinib Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Dasatinib Mesoridazine An increased risk of QT interval prolongation Details Dasatinib Mifepristone Korlym Increased dasatinib exposure and an increased risk of QT interval prolongation Details Dasatinib Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Dasatinib Pimozide An increased risk of QT interval prolongation Details Dasatinib Piperaquine Increased exposure of CYP3A4 substrates and an increased risk of QT interval prolongation Details Dasatinib Posaconazole Noxafil Increased CYP3A4 substrate exposure and an increased risk of QT interval prolongation Details Dasatinib Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Dasatinib Saquinavir An increased risk of QT interval prolongation Details Dasatinib Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Dasatinib Sparfloxacin An increased risk of QT interval prolongation Details Dasatinib Terfenadine An increased risk of QT interval prolongation Details Dasatinib Thioridazine An increased risk of QT interval prolongation Details Dasatinib Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Dasatinib Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Dasatinib Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details Dasatinib Ziprasidone Geodon An increased risk of QT interval prolongation Details

Major

Dasatinib Omeprazole Gastrobim Reduced dasatinib exposure Details Dasatinib Amitriptyline Elavil An increased risk of QT interval prolongation Details Dasatinib Sertraline An increased risk of QT interval prolongation Details Dasatinib Buprenorphine Belbuca An increased risk of QT interval prolongation Details Dasatinib Relugolix Orgovyx Increased risk of QT interval prolongation Details Dasatinib Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Dasatinib Arsenic Trioxide Trisenox An increased risk of QT interval prolongation Details Dasatinib Aripiprazole Injection Abilify An increased risk of QT interval prolongation Details Dasatinib Arsenic Trioxide Injection Trisenox An increased risk of QT interval prolongation Details Dasatinib Asciminib Scemblix Increased CYP3A4 exposure and an increased risk of CYP3A4-related adverse reactions Details Dasatinib Asenapine Transdermal Patch Secuado An increased risk of QT interval prolongation Details Dasatinib Azithromycin AzaSite An increased risk of QT interval prolongation Details Dasatinib Alfuzosin UroXatral An increased risk of QT interval prolongation Details Dasatinib Anagrelide Agrylin Increased risk of QT interval prolongation Details Dasatinib Bedaquiline Sirturo An increased risk of QT interval prolongation Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.