Calcium Silicate

Name: Calcium Silicate Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

15 interactions

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Cefuroxime Digoxin Hydroxychloroquine Infigratinib Ketoconazole Topical Octreotide

7 Major 8 Moderate

All (15) Major (7) Moderate (8)

Major

Calcium Silicate Cefuroxime Ceftin® Decreased cefuroxime axetil exposure Details Calcium Silicate Digoxin Cardoxin® Reduced digoxin exposure Details Calcium Silicate Hydroxychloroquine Plaquenil Reduced hydroxychloroquine exposure Details Calcium Silicate Infigratinib Truseltiq Decreased infigratinib plasma concentrations Details Calcium Silicate Ketoconazole Topical Extina® Foam Reduced ketoconazole exposure and reduced efficacy of ketoconazole Details Calcium Silicate Octreotide Bynfezia Decreased octreotide bioavailability Details Calcium Silicate Octreotide Injection Bynfezia Decreased octreotide bioavailability Details

Moderate

Calcium Silicate Bosutinib Bosulif Reduced bosutinib exposure Details Calcium Silicate Dasatinib Phyrago Reduced dasatinib exposure Details Calcium Silicate Demeclocycline Declomycin® Reduced efficacy of tetracyclines Details Calcium Silicate Doxycycline Injection Acticlate Reduced efficacy of tetracyclines Details Calcium Silicate Folic Acid Folacin Reduced folic acid exposure and reduced efficacy of folic acid Details Calcium Silicate Levothyroxine Ermeza Reduced efficacy of levothyroxine Details Calcium Silicate Minocycline Amzeeq Reduced efficacy of minocycline Details Calcium Silicate Minocycline Topical Amzeeq Reduced efficacy of minocycline Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.