Carvedilol

82 interactions 5 explained in plain English
Also sold as: Coreg Coreg® Coreg® CR
About Carvedilol

Carvedilol is a beta-blocker used to treat heart failure, high blood pressure, and recovery after a heart attack. Read the full Carvedilol drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Carvedilol Sertraline Explained Increased CYP2D6 substrate exposure Details Carvedilol Albuterol Oral Inhalation Accuneb® Explained Reduced efficacy of albuterol Details Carvedilol Relugolix Orgovyx Explained Increased relugolix exposure Details Carvedilol Betrixaban Bevyxxa® Increased betrixaban exposure and increased risk of bleeding Details Carvedilol Abiraterone Abirtega Increased CYP2D6 substrate exposure and an increased risk of CYP2D6 substrate-related adverse effects Details Carvedilol Afatinib Gilotrif Increased exposure of afatinib Details Carvedilol Capecitabine Xeloda Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Carvedilol Clonidine Transdermal Patch Catapres An increased risk of worsen sinus node dysfunction and atrioventricular node conduction, an increased risk of bradycardia and AV b... Details Carvedilol Dabigatran Pradaxa® Increased dabigatran exposure and an increased risk of bleeding Details Carvedilol Dabigatran Etexilate Increased dabigatran exposure and an increased risk of bleeding Details Carvedilol Digoxin Cardoxin® Increased digoxin exposure and an increased risk of bradycardia and advanced or complete heart block Details Carvedilol Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Carvedilol Fluorouracil Adrucil Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Carvedilol Fluorouracil Injection Adrucil Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Carvedilol Fluorouracil Topical Carac Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Carvedilol Indacaterol Oral Inhalation Arcapta® Decreased efficacy of indacaterol Details Carvedilol Lacosamide Injection Motpoly An increased risk of AV block, bradycardia, and ventricular tachyarrhythmia Details Carvedilol Lefamulin Xenleta Increased lefamulin exposure and an increased risk of lefamulin-related adverse reactions Details Carvedilol Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse effects Details Carvedilol Methylergonovine Methergine An increased risk of enhanced vasoconstrictive Details Carvedilol Miconazole Buccal Oravig Increased carvedilol concentrations and an increased risk of bradycardia or heart block Details Carvedilol Miconazole Topical Aloe Vesta Antifungal Increased carvedilol concentrations and an increased risk of bradycardia or heart block Details Carvedilol Miconazole Vaginal Lagicam Increased carvedilol concentrations and an increased risk of bradycardia or heart block Details Carvedilol Miconazole Aloe Vesta Antifungal Increased carvedilol concentrations and an increased risk of bradycardia or heart block Details Carvedilol Morphine Injection Astramorph® PF Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Carvedilol Olodaterol Oral Inhalation Striverdi Reduced olodaterol exposure and reduced beta-adrenergic blockers exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.