Granisetron Transdermal Patch

281 interactions 403 cited references

Also sold as: Sancuso Sancuso®

About Granisetron Transdermal Patch

Granisetron transdermal patches are used to prevent nausea and vomiting caused by chemotherapy. Granisetron is in a class of medications called 5HT3 inhibitors. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting. Read the full Granisetron Transdermal Patch drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Phenelzine Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine

16 Contraindicated 265 Major

All (281) Contraindicated (16) Major (265)

Contraindicated

Granisetron Transdermal Patch Apomorphine Apokyn Increased risk of profound hypotension and altered consciousness and an increased risk of QT interval prolongation, associated wit... Details Granisetron Transdermal Patch Bepridil An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Cisapride Propulsid® Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Dronedarone Multaq Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Fluconazole Diflucan Increased granisetron exposure and an increased risk of QT interval prolongation Details Granisetron Transdermal Patch Levoketoconazole Recorlev An increased risk of QT interval prolongation and an increased risk of torsade de pointes Details Granisetron Transdermal Patch Mesoridazine An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Phenelzine Nardil An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Pimozide An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Piperaquine An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Saquinavir An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Sparfloxacin An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Terfenadine An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Thioridazine An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Tranylcypromine Parnate An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Ziprasidone Geodon Increased risk of QT interval prolongation and an increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, men... Details

Major

Granisetron Transdermal Patch Adagrasib Krazati An increased risk of QT interval prolongation, torsade de pointes, polymorphic ventricular tachycardia, other serious arrhythmias Details Granisetron Transdermal Patch Alfentanil Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Alfuzosin UroXatral An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Almotriptan Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Amineptine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Amiodarone Nexterone An increased risk of QT interval prolongation and torsade de pointes Details Granisetron Transdermal Patch Amisulpride Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Granisetron Transdermal Patch Amitriptyline Elavil Increased risk of serotonin syndrome and QT-interval prolongation Details Granisetron Transdermal Patch Amitriptylinoxide Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Amoxapine Increased risk of serotonin syndrome and QT-interval prolongation Details Granisetron Transdermal Patch Amphetamine Dexedrine An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Anagrelide Agrylin Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Anileridine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Aripiprazole Abilify An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Aripiprazole Lauroxil Aristada An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Arsenic Trioxide Trisenox An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Artemether An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Asenapine Saphris Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Astemizole An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Atazanavir Reyataz An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Azithromycin AzaSite An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Bedaquiline Sirturo Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Benzhydrocodone An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Benzphetamine An increased risk of serotonin syndrome Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.