Magnesium

22 interactions
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Baloxavir Marboxil Dolutegravir
2 Major 20 Moderate
All (22) Major (2) Moderate (20)

Major

Magnesium Baloxavir Marboxil Xofluza Decreased baloxavir concentration Details Magnesium Dolutegravir Juluca® (as a combination product containing dolutegravir, rilpivirine) Reduced dolutegravir exposure and reduced efficacy of dolutegravir Details

Moderate

Magnesium Amikacin Injection Amikin® Neuromuscular weakness Details Magnesium Amikacin Oral Inhalation Arikayce Neuromuscular weakness Details Magnesium Deferiprone Ferriprox Decreased absorption of minerals Details Magnesium Delafloxacin Baxdela Decreased delafloxacin efficacy Details Magnesium Delafloxacin Injection Baxdela Decreased delafloxacin efficacy Details Magnesium Demeclocycline Declomycin® Reduced efficacy of tetracyclines Details Magnesium Doxercalciferol Hectoral® Hypermagnesemia Details Magnesium Doxercalciferol Injection Hectorol Hypermagnesemia Details Magnesium Doxycycline Injection Acticlate Reduced efficacy of tetracyclines Details Magnesium Felodipine Plendil® Hypotension Details Magnesium Folic Acid Folacin Reduced folic acid exposure and reduced efficacy of folic acid Details Magnesium Gatifloxacin Ophthalmic Zymar® Decreased gatifloxacin effectiveness Details Magnesium Gentamicin Injection Garamycin® I.V. Neuromuscular weakness Details Magnesium Gentamicin Ophthalmic Garamycin® Ophthalmic Neuromuscular weakness Details Magnesium Gentamicin Topical Garamycin® Neuromuscular weakness Details Magnesium Isradipine DynaCirc® Hypotension Details Magnesium Minocycline Amzeeq Reduced efficacy of minocycline Details Magnesium Minocycline Topical Amzeeq Reduced efficacy of minocycline Details Magnesium Nicardipine Cardene Hypotension Details Magnesium Nifedipine Adalat® Hypotension Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.