Zavegepant

Name: Zavegepant Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

6 interactions

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Cyclosporine Injection Cyclosporine Ophthalmic Darolutamide Gemfibrozil Leniolisib

5 Major 1 Moderate

All (6) Major (5) Moderate (1)

Major

Zavegepant Cyclosporine Injection Atopica Increased zavegepant exposure Details Zavegepant Cyclosporine Ophthalmic Cequa Increased zavegepant exposure Details Zavegepant Darolutamide Nubeqa Increased exposure of OATP1B1 or OATP1B3 substrates Details Zavegepant Gemfibrozil Lopid Increased zavegepant exposure Details Zavegepant Leniolisib Joenja Increased zavegepant exposure Details

Moderate

Zavegepant Encorafenib Braftovi Increased zavegepant exposure and increased risk of zavegepant-related toxicities Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.