Lixisenatide Injection

174 interactions 162 cited references

Also sold as: Adlyxin® Soliqua® (as a combination product containing Insulin Glargine and Lixisenatide)

About Lixisenatide Injection

Lixisenatide injection is used along with diet and exercise to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Lixisenatide injection is not used to treat type 1 diabetes (condition in which the body does not produce insuli… Read the full Lixisenatide Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Trovafloxacin Estradiol Enoxacin Drospirenone Dienogest Desogestrel

54 Major 120 Moderate

All (174) Major (54) Moderate (120)

Major

Lixisenatide Injection Abiraterone Acetate Abirtega An increased risk of severe hypoglycemia Details Lixisenatide Injection Abiraterone Acetate, Micronized Abirtega An increased risk of severe hypoglycemia Details Lixisenatide Injection Acetohexamide Increased risk of hypoglycemia Details Lixisenatide Injection Chloroquine Aralen® Hypoglycemia Details Lixisenatide Injection Chlorothiazide Diuril An increased risk of hyperglycemia and an increased insulin requirement Details Lixisenatide Injection Chlorpropamide Diabinese® Increased risk of hypoglycemia Details Lixisenatide Injection Chlorthalidone Hemiclor An increased risk of hyperglycemia and an increased insulin requirement Details Lixisenatide Injection Ciprofloxacin Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Delafloxacin Baxdela Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Desogestrel Decreased absorption of oral contraceptives Details Lixisenatide Injection Dienogest Decreased absorption of oral contraceptives Details Lixisenatide Injection Drospirenone Decreased absorption of oral contraceptives Details Lixisenatide Injection Enoxacin Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Estradiol Delestrogen Decreased absorption of oral contraceptives Details Lixisenatide Injection Ethinyl Estradiol Decreased absorption of oral contraceptives Details Lixisenatide Injection Ethynodiol Decreased absorption of oral contraceptives Details Lixisenatide Injection Etonogestrel Nexplanon Decreased absorption of oral contraceptives Details Lixisenatide Injection Furosemide Disal An increased risk of hyperglycemia and an increased insulin requirement Details Lixisenatide Injection Gatifloxacin Zymaxid Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Gemifloxacin Factive Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Gestodene Decreased absorption of oral contraceptives Details Lixisenatide Injection Gliclazide Increased risk of hypoglycemia Details Lixisenatide Injection Glimepiride Amaryl Increased risk of hypoglycemia Details Lixisenatide Injection Glipizide Glucotrol Increased risk of hypoglycemia Details Lixisenatide Injection Gliquidone Increased risk of hypoglycemia Details Lixisenatide Injection Glyburide DiaBeta® Increased risk of hypoglycemia Details Lixisenatide Injection Grepafloxacin Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Hydrochlorothiazide Inzirqo An increased risk of hyperglycemia and an increased insulin requirement Details Lixisenatide Injection Hydroflumethiazide An increased risk of hyperglycemia and an increased insulin requirement Details Lixisenatide Injection Hydroxychloroquine Plaquenil Enhanced hypoglycemic effect of antidiabetics and an increased risk of hypoglycemia Details Lixisenatide Injection Indapamide An increased risk of hyperglycemia and an increased insulin requirement Details Lixisenatide Injection Insulin Icodec-Abae Awiqli An increased risk of hypoglycemia Details Lixisenatide Injection Lanreotide Acetate An increased risk of hypoglycemia and impaired glucose regulation Details Lixisenatide Injection Levofloxacin Levaquin Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Levonorgestrel After banger Decreased absorption of oral contraceptives Details Lixisenatide Injection Lomefloxacin Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Mestranol Decreased absorption of oral contraceptives Details Lixisenatide Injection Metolazone An increased risk of hyperglycemia and an increased insulin requirement Details Lixisenatide Injection Moxifloxacin Avelox Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Norethindrone Aygestin Decreased absorption of oral contraceptives Details

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