Lixisenatide Injection

174 interactions 162 cited references

Also sold as: Adlyxin® Soliqua® (as a combination product containing Insulin Glargine and Lixisenatide)

About Lixisenatide Injection

Lixisenatide injection is used along with diet and exercise to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Lixisenatide injection is not used to treat type 1 diabetes (condition in which the body does not produce insuli… Read the full Lixisenatide Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Trovafloxacin Estradiol Enoxacin Drospirenone Dienogest Desogestrel

54 Major 120 Moderate

All (174) Major (54) Moderate (120)

Major

Lixisenatide Injection Norfloxacin Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Norgestimate Decreased absorption of oral contraceptives Details Lixisenatide Injection Norgestrel Decreased absorption of oral contraceptives Details Lixisenatide Injection Octreotide Acetate An increased risk of hypoglycemia and impaired glucose regulation Details Lixisenatide Injection Ofloxacin Floxin® Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Pasireotide Diaspartate An increased risk of hypoglycemia and impaired glucose regulation Details Lixisenatide Injection Polythiazide An increased risk of hyperglycemia and an increased insulin requirement Details Lixisenatide Injection Somatrogon-Ghla Reduced insulin sensitivity Details Lixisenatide Injection Sparfloxacin Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Lixisenatide Injection Thioctic Acid Increased risk of hypoglycemia Details Lixisenatide Injection Tolazamide Tolinase® Increased risk of hypoglycemia Details Lixisenatide Injection Tolbutamide Orinase® Increased risk of hypoglycemia Details Lixisenatide Injection Triamterene Dyrenium An increased risk of hyperglycemia and an increased insulin requirement Details Lixisenatide Injection Trovafloxacin Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details

Moderate

Lixisenatide Injection Acebutolol Sectral® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Acetaminophen Acephen Slowed absorption of acetaminophen Details Lixisenatide Injection Amoxicillin Amoxi Drop Delayed therapeutic effect Details Lixisenatide Injection Ampicillin Amcill® Delayed therapeutic effect Details Lixisenatide Injection Atenolol Tenormin Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Azanidazole Delayed therapeutic effect Details Lixisenatide Injection Bacampicillin Delayed therapeutic effect Details Lixisenatide Injection Balofloxacin Delayed therapeutic effect Details Lixisenatide Injection Benazepril Lotensin An increased risk of hypoglycemia Details Lixisenatide Injection Benznidazole Delayed therapeutic effect Details Lixisenatide Injection Betaxolol Betoptic S Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Bisoprolol Zebeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Captopril Capoten® An increased risk of hypoglycemia Details Lixisenatide Injection Carteolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Carvedilol Coreg Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Lixisenatide Injection Cefaclor Ceclor® Delayed therapeutic effect Details Lixisenatide Injection Cefadroxil Duricef® Delayed therapeutic effect Details Lixisenatide Injection Cefatrizine Delayed therapeutic effect Details Lixisenatide Injection Cefdinir Omnicef® Delayed therapeutic effect Details Lixisenatide Injection Cefditoren Spectracef® Delayed therapeutic effect Details Lixisenatide Injection Cefetamet Delayed therapeutic effect Details Lixisenatide Injection Cefixime Suprax Delayed therapeutic effect Details Lixisenatide Injection Cefpodoxime Banan® Delayed therapeutic effect Details Lixisenatide Injection Cefprozil Cefzil® Delayed therapeutic effect Details Lixisenatide Injection Cefteram Pivoxil Delayed therapeutic effect Details Lixisenatide Injection Ceftibuten Cedax® Delayed therapeutic effect Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.