Rifampin

Contraindicated

Rifampin Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of colchicine toxicity Details Rifampin Aficamten Reduced aficamten exposure and an reduced risk of aficamten-related adverse reaction Details Rifampin Cabotegravir Apretude Decreased cabotegravir plasma concentration with loss of virologic response. Details Rifampin Doravirine Pifeltro Reduced doravirine exposure, reduced efficacy of doravirine and an increased risk of doravirine resistance Details Rifampin Fostemsavir Rukobia Reduced temsavir (the active moiety of fostemsavir) exposure and possible loss of virologic response Details Rifampin Lenacapavir Injection Sunlenca Reduced lenacapavir exposure which may result in the loss of therapeutic effect and development of resistance to lenacapavir Details Rifampin Lenacapavir Oral Sunlenca Reduced lenacapavir exposure which may result in the loss of therapeutic effect and development of resistance to lenacapavir Details Rifampin Lurasidone Latuda Reduced lurasidone exposure Details Rifampin Nifedipine Adalat® Reduced NIFEdipine exposure and reduced efficacy of NIFEdipine Details

Major

Rifampin Acetaminophen And Codeine Capital® & Codeine Explained Reduced codeine and morphine exposure, reduced opioid efficacy and precipitation of opioid withdrawal Details Rifampin Omeprazole Gastrobim Explained Reduced omeprazole exposure Details Rifampin Buprenorphine Belbuca Explained Reduced buprenorphine exposure and reduced efficacy of buprenorphine Details Rifampin Relugolix Orgovyx Explained Altered relugolix exposure, an increased risk of relugolix-related adverse reactions and reduced efficacy of relugolix Details Rifampin Simvastatin Flolipid Explained Reduced simvastatin exposure and reduced efficacy of simvastatin Details Rifampin Abemaciclib Verzenio Explained Decreased abemaciclib plasma concentration Details Rifampin Abrocitinib Cibinqo Explained Decreased abrocitinib and active metabolite exposure Details Rifampin Acalabrutinib Calquence Reduced acalabrutinib exposure Details Rifampin Alpelisib Piqray Reduced alpelisib exposure and reduced efficacy of alpelisib Details Rifampin Apixaban Eliquis Explained Reduced apixaban exposure, reduced efficacy of apixaban and an increased risk of stroke and other thromboembolic events Details Rifampin Apremilast Otezla Reduced apremilast exposure and an reduced efficacy of apremilast Details Rifampin Aripiprazole Injection Abilify Reduced ARIPiprazole exposure Details Rifampin Asciminib Scemblix Reduced asciminib exposure and reduced efficacy of asciminib Details Rifampin Atogepant Qulipta Altered atogepant exposure Details Rifampin Atovaquone Mepron Reduced atovaquone exposure, an increased rifAMPin exposure and an increased risk of rifAMPin-related adverse reactions Details Rifampin Avapritinib Ayvakit Reduced avapritinib exposure and reduced efficacy of avapritinib Details Rifampin Avatrombopag Doptelet Decreased avatrombopag exposure Details Rifampin Azathioprine Azasan An increased risk of hepatotoxicity Details Rifampin Belumosudil Rezurock Explained Reduced belumosudil exposure and reduced efficacy of belumosudil Details Rifampin Betrixaban Bevyxxa® Decreased betrixaban exposure Details Rifampin Cariprazine Vraylar Explained Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Rifampin Abiraterone Abirtega Reduced abiraterone exposure and reduced efficacy of abiraterone Details Rifampin Afatinib Gilotrif Decreased afatinib exposure Details Rifampin Amlodipine Amvaz® Reduced amLODIPine exposure Details Rifampin Axitinib Inlyta Reduced axitinib exposure Details Rifampin Bedaquiline Sirturo Reduced bedaquiline exposure and reduced efficacy of bedaquiline Details Rifampin Bendamustine Injection Belrapzo Reduced bendamustine exposure and reduced efficacy of bendamustine Details Rifampin Bortezomib Boruzu Reduced bortezomib exposure Details Rifampin Bosutinib Bosulif Reduced bosutinib exposure and reduced efficacy of bosutinib Details Rifampin Brexpiprazole Rexulti Reduced brexpiprazole exposure Details Rifampin Brigatinib Alunbrig Reduced brigatinib efficacy Details