Azacitidine

21 interactions 118 cited references
Also sold as: Onureg Onureg® Vidaza
About Azacitidine

Azacitidine is used to treat acute myeloid leukemia (AML; cancer of the white blood cells) in adults who improved after chemotherapy, but who are unable to complete intensive curative therapy. Azacitidine is in a class of medications called demethylation agents. It works by helping the bone marrow to produce normal blo… Read the full Azacitidine drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Smallpox Monkeypox Vaccine Rubella Virus Vaccine, Live Typhoid Vaccine Bacillus Of Calmette And Guerin Vaccine, Live Varicella Virus Vaccine, Live Yellow Fever Vaccine
9 Contraindicated 12 Major
All (21) Contraindicated (9) Major (12)

Contraindicated

Azacitidine Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Azacitidine Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Azacitidine Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Azacitidine Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Azacitidine Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Azacitidine Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Azacitidine Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Azacitidine Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Azacitidine Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Azacitidine Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Azacitidine Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Azacitidine Azathioprine Azasan An increased risk of hepatotoxicity Details Azacitidine Cedazuridine Increased exposure of cytidine deaminase substrates and increased risk of toxicity Details Azacitidine Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Azacitidine Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Azacitidine Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Azacitidine Levoketoconazole Recorlev Increased risk of serious hepatotoxicity and drug-induced liver injury Details Azacitidine Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Azacitidine Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Azacitidine Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details Azacitidine Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details

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