Sparfloxacin

92 interactions 5 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Felbamate Sertraline Oxaliplatin Injection Eribulin Injection Dasatinib Levofloxacin Injection

63 Contraindicated 28 Major 1 Moderate

All (92) Contraindicated (63) Major (28) Moderate (1)

Contraindicated

Sparfloxacin Amitriptyline Elavil Explained An increased risk of QT interval prolongation Details Sparfloxacin Sertraline Explained An increased risk of QT interval prolongation Details Sparfloxacin Buprenorphine Belbuca Explained An increased risk of QT interval prolongation Details Sparfloxacin Relugolix Orgovyx Explained An increased risk of QT interval prolongation Details Sparfloxacin Amisulpride Injection Barhemsys An increased risk of QT interval prolongation Details Sparfloxacin Arsenic Trioxide Trisenox An increased risk of QT interval prolongation Details Sparfloxacin Aripiprazole Injection Abilify An increased risk of QT interval prolongation Details Sparfloxacin Arsenic Trioxide Injection Trisenox An increased risk of QT interval prolongation Details Sparfloxacin Asenapine Transdermal Patch Secuado An increased risk of QT interval prolongation Details Sparfloxacin Azithromycin AzaSite An increased risk of QT interval prolongation Details Sparfloxacin Alfuzosin UroXatral An increased risk of QT interval prolongation Details Sparfloxacin Anagrelide Agrylin An increased risk of QT interval prolongation Details Sparfloxacin Bedaquiline Sirturo An increased risk of QT interval prolongation Details Sparfloxacin Chloroquine Aralen® An increased risk of QT interval prolongation Details Sparfloxacin Dasatinib Phyrago An increased risk of QT interval prolongation Details Sparfloxacin Degarelix Injection Firmagon An increased risk of QT interval prolongation Details Sparfloxacin Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Sparfloxacin Disopyramide Norpace An increased risk of QT interval prolongation Details Sparfloxacin Dofetilide Tikosyn An increased risk of QT interval prolongation Details Sparfloxacin Dolasetron Anzemet An increased risk of QT interval prolongation Details Sparfloxacin Dolasetron Injection Anzemet An increased risk of QT interval prolongation Details Sparfloxacin Encorafenib Braftovi An increased risk of QT interval prolongation Details Sparfloxacin Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Sparfloxacin Eribulin Injection Halaven An increased risk of QT interval prolongation Details Sparfloxacin Famotidine Calmicid An increased risk of QT interval prolongation Details Sparfloxacin Famotidine Injection Calmicid An increased risk of QT interval prolongation Details Sparfloxacin Felbamate Felbatol An increased risk of QT interval prolongation Details Sparfloxacin Flecainide Tambocor® An increased risk of QT interval prolongation Details Sparfloxacin Foscarnet Injection Foscavir An increased risk of QT interval prolongation Details Sparfloxacin Fostemsavir Rukobia An increased risk of QT interval prolongation Details Sparfloxacin Galantamine Razadyne An increased risk of QT interval prolongation Details Sparfloxacin Gatifloxacin Ophthalmic Zymar® An increased risk of QT interval prolongation Details Sparfloxacin Gemifloxacin Factive An increased risk of QT interval prolongation Details Sparfloxacin Glasdegib Daurismo An increased risk of QT interval prolongation Details Sparfloxacin Goserelin Implant Zoladex An increased risk of QT interval prolongation Details Sparfloxacin Granisetron Transdermal Patch Sancuso An increased risk of QT interval prolongation Details Sparfloxacin Granisetron Injection Granisol An increased risk of QT interval prolongation Details Sparfloxacin Histrelin Implant Supprelin An increased risk of QT interval prolongation Details Sparfloxacin Hydroxychloroquine Plaquenil An increased risk of QT interval prolongation Details Sparfloxacin Inotuzumab Ozogamicin Injection Besponsa An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.