Potassium Citrate

45 interactions 3 explained in plain English

Also sold as: Urocit-K

Read the full Potassium Citrate drug information page

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Amitriptyline Cyclopentolate Ophthalmic Trospium / Xanomeline Glycopyrronium Topical Diphenhydramine Injection Ipratropium Nasal Spray

10 Contraindicated 35 Major

All (45) Contraindicated (10) Major (35)

Contraindicated

Potassium Citrate Amitriptyline Elavil Explained Increased risk of gastrointestinal irritation Details Potassium Citrate Trospium / Xanomeline Cobenfy Explained Increased risk of gastrointestinal irritation Details Potassium Citrate Aclidinium Oral Inhalation Tudorza Increased risk of gastrointestinal irritation Details Potassium Citrate Atropine Ophthalmic Atropine Care 1% Increased risk of gastrointestinal irritation Details Potassium Citrate Cyclopentolate Ophthalmic Akpentolate® Increased risk of gastrointestinal irritation Details Potassium Citrate Diphenhydramine Injection Banophen Increased risk of gastrointestinal irritation Details Potassium Citrate Diphenhydramine Topical Afterbite with Antihistamine Increased risk of gastrointestinal irritation Details Potassium Citrate Glycopyrronium Topical Cuvposa® Increased risk of gastrointestinal irritation Details Potassium Citrate Ipratropium Nasal Spray Atrovent Nasal Spray® Increased risk of gastrointestinal irritation Details Potassium Citrate Ipratropium Oral Inhalation Atrovent® HFA Increased risk of gastrointestinal irritation Details

Major

Potassium Citrate Lisinopril Prinivil Explained Increased risk of hyperkalemia Details Potassium Citrate Aliskiren Tekturna Increased risk of hyperkalemia Details Potassium Citrate Aspirin Acuprin® Increased risk of hyperkalemia Details Potassium Citrate Aspirin Rectal Aspirin Increased risk of hyperkalemia Details Potassium Citrate Benazepril Lotensin Increased risk of hyperkalemia Details Potassium Citrate Azilsartan Edarbi Increased risk of hyperkalemia Details Potassium Citrate Bromfenac Ophthalmic Bromday® Increased risk of hyperkalemia Details Potassium Citrate Captopril Capoten® Increased risk of hyperkalemia Details Potassium Citrate Diclofenac Ophthalmic Voltaren® Eye Drops Increased risk of hyperkalemia Details Potassium Citrate Diclofenac Topical (Actinic Keratosis) Pennsaid Increased risk of hyperkalemia Details Potassium Citrate Diclofenac Topical (Arthritis Pain) Pennsaid® Increased risk of hyperkalemia Details Potassium Citrate Diclofenac Transdermal Patch Flector Increased risk of hyperkalemia Details Potassium Citrate Enalapril Epaned Increased risk of hyperkalemia Details Potassium Citrate Eprosartan Teveten® Increased risk of hyperkalemia Details Potassium Citrate Etodolac Lodine Increased risk of hyperkalemia Details Potassium Citrate Fenoprofen Fenopron Increased risk of hyperkalemia Details Potassium Citrate Flurbiprofen Ansaid Increased risk of hyperkalemia Details Potassium Citrate Flurbiprofen Ophthalmic Ocufen Increased risk of hyperkalemia Details Potassium Citrate Fosinopril Monopril® Increased risk of hyperkalemia Details Potassium Citrate Ibuprofen Addaprin Increased risk of hyperkalemia Details Potassium Citrate Irbesartan Avapro Increased risk of hyperkalemia Details Potassium Citrate Ketoprofen Actron® Increased risk of hyperkalemia Details Potassium Citrate Ketorolac Acular Increased risk of hyperkalemia Details Potassium Citrate Ketorolac Injection Acular Increased risk of hyperkalemia Details Potassium Citrate Ketorolac Nasal Spray Sprix Increased risk of hyperkalemia Details Potassium Citrate Ketorolac Ophthalmic Acular Increased risk of hyperkalemia Details Potassium Citrate Losartan Arbli Increased risk of hyperkalemia Details Potassium Citrate Meclofenamate Meclodium® Increased risk of hyperkalemia Details Potassium Citrate Mefenamic Acid Ponstel® Increased risk of hyperkalemia Details Potassium Citrate Meloxicam Alloxate Increased risk of hyperkalemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.