Sulodexide

42 interactions 2 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Sertraline Ibuprofen Aspirin Epoprostenol Etodolac Orlistat

38 Major 4 Moderate

All (42) Major (38) Moderate (4)

Major

Sulodexide Sertraline Explained An increased risk of bleeding Details Sulodexide Apixaban Eliquis Explained An increased risk of bleeding and can cause serious, potentially fatal bleeding Details Sulodexide Aspirin Acuprin® Increased risk of bleeding Details Sulodexide Aspirin Rectal Aspirin Increased risk of bleeding Details Sulodexide Betrixaban Bevyxxa® Increased risk of bleeding Details Sulodexide Anagrelide Agrylin Increased risk of bleeding Details Sulodexide Bromfenac Ophthalmic Bromday® An increased risk of bleeding Details Sulodexide Clopidogrel Plavix Increased risk of bleeding Details Sulodexide Dabigatran Pradaxa® An increased risk of bleeding Details Sulodexide Dabigatran Etexilate An increased risk of bleeding Details Sulodexide Diclofenac Ophthalmic Voltaren® Eye Drops An increased risk of bleeding Details Sulodexide Diclofenac Topical (Actinic Keratosis) Pennsaid An increased risk of bleeding Details Sulodexide Diclofenac Topical (Arthritis Pain) Pennsaid® An increased risk of bleeding Details Sulodexide Diclofenac Transdermal Patch Flector An increased risk of bleeding Details Sulodexide Dipyridamole Permole® Increased risk of bleeding Details Sulodexide Doxycycline Injection Acticlate An increased risk of bleeding Details Sulodexide Epoprostenol Flolan Increased risk of bleeding Details Sulodexide Etodolac Lodine An increased risk of bleeding Details Sulodexide Fenoprofen Fenopron An increased risk of bleeding Details Sulodexide Flurbiprofen Ansaid An increased risk of bleeding Details Sulodexide Flurbiprofen Ophthalmic Ocufen An increased risk of bleeding Details Sulodexide Ibuprofen Addaprin An increased risk of bleeding Details Sulodexide Iloprost Aurlumyn Increased risk of bleeding Details Sulodexide Ketoprofen Actron® An increased risk of bleeding Details Sulodexide Ketorolac Acular An increased risk of bleeding Details Sulodexide Ketorolac Injection Acular An increased risk of bleeding Details Sulodexide Ketorolac Nasal Spray Sprix An increased risk of bleeding Details Sulodexide Ketorolac Ophthalmic Acular An increased risk of bleeding Details Sulodexide Lecanemab-Irmb Injection Leqembi An increased risk of amyloid related imaging abnormalities (ARIA), or intracerebral hemorrhage Details Sulodexide Meclofenamate Meclodium® An increased risk of bleeding Details Sulodexide Mefenamic Acid Ponstel® An increased risk of bleeding Details Sulodexide Meloxicam Alloxate An increased risk of bleeding Details Sulodexide Meloxicam Injection Alloxate An increased risk of bleeding Details Sulodexide Minocycline Amzeeq An increased risk of bleeding Details Sulodexide Minocycline Topical Amzeeq An increased risk of bleeding Details Sulodexide Nabumetone Relafen An increased risk of bleeding Details Sulodexide Naproxen Aleve An increased risk of bleeding Details Sulodexide Orlistat Alli An increased risk of bleeding Details

Moderate

Sulodexide Capsaicin Arthricare for Women Moisturizing Increased risk of bleeding Details Sulodexide Capsaicin Topical Aspercreme Warming® Increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.