Amprenavir

Contraindicated

Amprenavir Simvastatin Flolipid Explained An increased risk of myopathy or rhabdomyolysis Details Amprenavir Dihydroergotamine Injection DHE-45® Injection Increased dihydroergotamine exposure and an increased risk of ergotism (nausea, vomiting, peripheral vasospasm, and peripheral isc... Details Amprenavir Dihydroergotamine Nasal Spray Migranal Increased dihydroergotamine exposure and an increased risk of ergotism (nausea, vomiting, peripheral vasospasm, and peripheral isc... Details Amprenavir Disulfiram Antabuse An increased risk of propylene glycol toxicity (seizures, tachycardia, lactic acidosis, renal toxicity, hemolysis) Details Amprenavir Lovastatin Altocor® Increased plasma levels of lovastatin and an increased risk of myopathy or rhabdomyolysis Details Amprenavir Metronidazole Flagyl An increased risk of propylene glycol toxicity (seizures, tachycardia, lactic acidosis, renal toxicity, hemolysis) Details Amprenavir Metronidazole Injection Flagyl An increased risk of propylene glycol toxicity (seizures, tachycardia, lactic acidosis, renal toxicity, hemolysis) Details Amprenavir Metronidazole Topical MetroCream® An increased risk of propylene glycol toxicity (seizures, tachycardia, lactic acidosis, renal toxicity, hemolysis) Details Amprenavir Metronidazole Vaginal MetroGel® Vaginal An increased risk of propylene glycol toxicity (seizures, tachycardia, lactic acidosis, renal toxicity, hemolysis) Details Amprenavir Midazolam Nasal Spray Nayzilam An increased risk of midazolam toxicity (excessive sedation, confusion) Details Amprenavir Midazolam Injection Nayzilam An increased risk of midazolam toxicity (excessive sedation, confusion) Details

Major

Amprenavir Acetaminophen And Codeine Capital® & Codeine Explained Increased codeine and morphine exposure Details Amprenavir Abametapir Explained Increased exposure of CYP3A4 substrate Details Amprenavir Buprenorphine Belbuca Explained Increased buprenorphine exposure and an increased risk of buprenorphine-related adverse events Details Amprenavir Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of fatal toxicity Details Amprenavir Atogepant Qulipta Reduced atogepant exposure Details Amprenavir Avapritinib Ayvakit Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Amprenavir Atorvastatin Atorvaliq Increased atorvastatin exposure and an increased risk of myopathy or rhabdomyolysis Details Amprenavir Cariprazine Vraylar Explained Increased cariprazine and its major active metabolite (didesmethylcariprazine (DDCAR)) exposure Details Amprenavir Amlodipine Amvaz® Increased amLODIPine exposure, an increased risk of hypotension and edema and reduced amLODIPine exposure Details Amprenavir Bedaquiline Sirturo Increased bedaquiline exposure Details Amprenavir Bosutinib Bosulif Increased bosutinib exposure Details Amprenavir Brexpiprazole Rexulti Increased brexpiprazole exposure Details Amprenavir Budesonide Entocort Increased budesonide exposure Details Amprenavir Budesonide Nasal Spray Rhinocort Increased budesonide exposure Details Amprenavir Budesonide Oral Inhalation Pulmicort Increased budesonide exposure Details Amprenavir Cabotegravir Apretude Loss of virologic response and possible development of viral resistance Details Amprenavir Cyclophosphamide Cytoxan® Increased risk of chemotherapy-induced mucositis, neutropenia, and infection Details Amprenavir Cyclophosphamide Injection Cytoxan® Injection Increased risk of chemotherapy-induced mucositis, neutropenia, and infection Details Amprenavir Cyclosporine Injection Atopica Increased cycloSPORINE exposure Details Amprenavir Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure Details Amprenavir Dolutegravir Juluca® (as a combination product containing dolutegravir, rilpivirine) Reduced dolutegravir exposure and reduced efficacy of dolutegravir Details Amprenavir Doxorubicin Adriamycin Increased doxorubicin exposure and an increased risk of doxorubicin-related adverse reactions Details Amprenavir Encorafenib Braftovi Increased encorafenib exposure and an increased risk of encorafenib-related adverse events Details Amprenavir Entrectinib Rozlytrek Increased entrectinib exposure and an increased frequency or severity of adverse reactions Details Amprenavir Estradiol Delestrogen Reduced amprenavir exposure, altered hormonal levels, loss of contraceptive efficacy, and an increased risk of liver enzyme elevat... Details Amprenavir Estradiol Topical Divigel Reduced amprenavir exposure, altered hormonal levels, loss of contraceptive efficacy, and an increased risk of liver enzyme elevat... Details Amprenavir Estradiol Transdermal Patch Alora® Reduced amprenavir exposure, altered hormonal levels, loss of contraceptive efficacy, and an increased risk of liver enzyme elevat... Details Amprenavir Famotidine Calmicid Decreased fosamprenavir absorption and reduction of amprenavir efficacy (active fosamprenavir metabolite) Details Amprenavir Famotidine Injection Calmicid Decreased fosamprenavir absorption and reduction of amprenavir efficacy (active fosamprenavir metabolite) Details