Mirabegron

16 interactions 4 explained in plain English
Also sold as: Myrbetriq
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Colchicine Acetaminophen And Codeine Relugolix Brexpiprazole Cyclosporine Injection Cyclosporine Ophthalmic
1 Contraindicated 12 Major 3 Moderate
All (16) Contraindicated (1) Major (12) Moderate (3)

Contraindicated

Mirabegron Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of colchicine toxicity Details

Major

Mirabegron Acetaminophen And Codeine Capital® & Codeine Explained Increased codeine exposure and reduced active metabolite (morphine) exposure Details Mirabegron Relugolix Orgovyx Explained Increased relugolix exposure Details Mirabegron Brexpiprazole Rexulti Increased brexpiprazole exposure Details Mirabegron Cyclosporine Injection Atopica Increased cycloSPORINE exposure Details Mirabegron Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure Details Mirabegron Dabigatran Pradaxa® Increased dabigatran exposure and an increased risk of bleeding Details Mirabegron Dabigatran Etexilate Increased dabigatran exposure and an increased risk of bleeding Details Mirabegron Digoxin Cardoxin® Increased digoxin exposure Details Mirabegron Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Mirabegron Lefamulin Xenleta Increased lefamulin exposure and an increased risk of lefamulin-related adverse reactions Details Mirabegron Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse effects Details Mirabegron Morphine Injection Astramorph® PF Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details

Moderate

Mirabegron Amitriptyline Elavil Explained Increased amitriptyline exposure Details Mirabegron Flecainide Tambocor® Increased flecainide exposure Details Mirabegron Mexiletine Mexitil® Increased mexiletine plasma concentrations Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.