Brinzolamide Ophthalmic

Name: Brinzolamide Ophthalmic Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

5 interactions 112 cited references

Also sold as: Azopt Azopt®

About Brinzolamide Ophthalmic

Ophthalmic Brinzolamide is used to treat glaucoma, a condition that increases pressure in the eye and leads to vision loss. Brinzolamide is in a class of medications called carbonic anhydrase inhibitors. It decreases the pressure in the eye. Read the full Brinzolamide Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Aspirin Ceritinib Memantine Metformin Topiramate

5 Major

All (5) Major (5)

Major

Brinzolamide Ophthalmic Aspirin Acuprin® Increased carbonic anhydrase inhibitors exposure and its toxicity Details Brinzolamide Ophthalmic Ceritinib Zykadia Increased CYP3A substrate exposure Details Brinzolamide Ophthalmic Memantine Namenda Reduced clearance of memantine Details Brinzolamide Ophthalmic Metformin Fortamet® An increased risk of lactic acidosis and reduced serum bicarbonate Details Brinzolamide Ophthalmic Topiramate Eprontia An increased risk of nephrolithiasis and severity of metabolic acidosis Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.