Levalbuterol

16 interactions 3 explained in plain English
Also sold as: Xopenex
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Nebivolol Labetalol Levobunolol Ophthalmic Nadolol Esmolol Olodaterol Oral Inhalation
14 Major 2 Moderate
All (16) Major (14) Moderate (2)

Major

Levalbuterol Amitriptyline Elavil Explained An increased risk of cardiovascular system effects (eg, tachycardia, blood pressure changes) Details Levalbuterol Albuterol Oral Inhalation Accuneb® Explained Increased risk of adverse cardiovascular effects Details Levalbuterol Atenolol Tenormin Explained Reduced efficacy of levalbuterol Details Levalbuterol Acebutolol Sectral® Reduced efficacy of levalbuterol Details Levalbuterol Betaxolol Betoptic S Reduced efficacy of levalbuterol Details Levalbuterol Betaxolol Ophthalmic Betoptic® Reduced efficacy of levalbuterol Details Levalbuterol Bisoprolol Zebeta® Reduced efficacy of levalbuterol Details Levalbuterol Esmolol Brevibloc Reduced efficacy of levalbuterol Details Levalbuterol Labetalol Normodyne® Reduced efficacy of levalbuterol Details Levalbuterol Levobunolol Ophthalmic AKBeta® Reduced efficacy of levalbuterol Details Levalbuterol Nadolol Corgard Reduced efficacy of levalbuterol Details Levalbuterol Nebivolol Bystolic Reduced efficacy of levalbuterol Details Levalbuterol Olodaterol Oral Inhalation Striverdi An increased risk of clinically significant cardiovascular effects and fatalities and an increased/potentiated sympathetic effects... Details Levalbuterol Penbutolol Levatol® Reduced efficacy of levalbuterol Details

Moderate

Levalbuterol Digoxin Cardoxin® Decreased digoxin serum concentrations Details Levalbuterol Furosemide Injection Disal ECG changes or hypokalemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.