Proglumetacin
91 interactions 5 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Ketorolac Nasal Spray
Ketorolac
Ketorolac Ophthalmic
Ketorolac Injection
Pemetrexed Injection
Edoxaban
Contraindicated
Proglumetacin Ketorolac Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Proglumetacin Ketorolac Injection Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Proglumetacin Ketorolac Nasal Spray Sprix Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Proglumetacin Ketorolac Ophthalmic Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) DetailsMajor
Proglumetacin Amitriptyline Elavil Explained An increased risk of bleeding Details Proglumetacin Sertraline Explained An increased risk of bleeding Details Proglumetacin Apixaban Eliquis Explained An increased risk of bleeding Details Proglumetacin Aspirin Acuprin® An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Proglumetacin Aspirin Rectal Aspirin An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Proglumetacin Betrixaban Bevyxxa® An increased risk of bleeding Details Proglumetacin Anagrelide Agrylin An increased risk of bleeding Details Proglumetacin Bromfenac Ophthalmic Bromday® Increased risk of bleeding Details Proglumetacin Budesonide Entocort Increased risk of gastrointestinal ulcer or bleeding Details Proglumetacin Budesonide Nasal Spray Rhinocort Increased risk of gastrointestinal ulcer or bleeding Details Proglumetacin Budesonide Oral Inhalation Pulmicort Increased risk of gastrointestinal ulcer or bleeding Details Proglumetacin Clopidogrel Plavix An increased risk of bleeding Details Proglumetacin Cyclosporine Injection Atopica An increased risk of cycloSPORINE nephrotoxicity Details Proglumetacin Cyclosporine Ophthalmic Cequa An increased risk of cycloSPORINE nephrotoxicity Details Proglumetacin Dabigatran Pradaxa® An increased risk of bleeding Details Proglumetacin Dabigatran Etexilate An increased risk of bleeding Details Proglumetacin Dalteparin Injection Fragmin An increased risk of bleeding Details Proglumetacin Deflazacort Emflaza Increased risk of gastrointestinal ulcer or bleeding Details Proglumetacin Dexamethasone Injection Decadron Increased risk of gastrointestinal ulcer or bleeding Details Proglumetacin Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Increased risk of gastrointestinal ulcer or bleeding Details Proglumetacin Diclofenac Ophthalmic Voltaren® Eye Drops Increased risk of bleeding Details Proglumetacin Diclofenac Topical (Actinic Keratosis) Pennsaid Increased risk of bleeding Details Proglumetacin Diclofenac Topical (Arthritis Pain) Pennsaid® Increased risk of bleeding Details Proglumetacin Diclofenac Transdermal Patch Flector Increased risk of bleeding Details Proglumetacin Digoxin Cardoxin® Increased digoxin exposure and prolonged half-life of digoxin Details Proglumetacin Dipyridamole Permole® An increased risk of bleeding Details Proglumetacin Edoxaban Savaysa An increased risk of bleeding Details Proglumetacin Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Proglumetacin Enoxaparin Lovenox An increased risk of bleeding Details Proglumetacin Enoxaparin Injection Lovenox An increased risk of bleeding Details Proglumetacin Epoprostenol Flolan An increased risk of bleeding Details Proglumetacin Etodolac Lodine Increased risk of bleeding Details Proglumetacin Fenoprofen Fenopron Increased risk of bleeding Details Proglumetacin Flurbiprofen Ansaid Increased risk of bleeding Details Proglumetacin Flurbiprofen Ophthalmic Ocufen Increased risk of bleeding Details Proglumetacin Fondaparinux Arixtra An increased risk of bleeding DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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