Proglumetacin

91 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Nasal Spray Ketorolac Ketorolac Ophthalmic Ketorolac Injection Pemetrexed Injection Edoxaban
4 Contraindicated 59 Major 28 Moderate
All (91) Contraindicated (4) Major (59) Moderate (28)

Moderate

Proglumetacin Lisinopril Prinivil Explained Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Proglumetacin Atenolol Tenormin Explained Reduced antihypertensive effect Details Proglumetacin Acebutolol Sectral® Reduced antihypertensive effect Details Proglumetacin Benazepril Lotensin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Proglumetacin Azilsartan Edarbi Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Proglumetacin Betaxolol Betoptic S Reduced antihypertensive effect Details Proglumetacin Betaxolol Ophthalmic Betoptic® Reduced antihypertensive effect Details Proglumetacin Bisoprolol Zebeta® Reduced antihypertensive effect Details Proglumetacin Captopril Capoten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Proglumetacin Desmopressin Nasal Concentraid® Increased risk of water intoxication with hyponatremia Details Proglumetacin Enalapril Epaned Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Proglumetacin Eprosartan Teveten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Proglumetacin Esmolol Brevibloc Reduced antihypertensive effect Details Proglumetacin Fosinopril Monopril® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Proglumetacin Irbesartan Avapro Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Proglumetacin Labetalol Normodyne® Reduced antihypertensive effect Details Proglumetacin Levobunolol Ophthalmic AKBeta® Reduced antihypertensive effect Details Proglumetacin Levofloxacin Levaquin An increased risk of seizures Details Proglumetacin Levofloxacin Injection Levaquin An increased risk of seizures Details Proglumetacin Losartan Arbli Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Proglumetacin Moexipril Univasc® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Proglumetacin Nadolol Corgard Reduced antihypertensive effect Details Proglumetacin Nebivolol Bystolic Reduced antihypertensive effect Details Proglumetacin Ofloxacin Floxin® An increased risk of seizures Details Proglumetacin Ofloxacin Ophthalmic Ocuflox An increased risk of seizures Details Proglumetacin Ofloxacin Otic Floxin® Otic An increased risk of seizures Details Proglumetacin Penbutolol Levatol® Reduced antihypertensive effect Details Proglumetacin Perindopril Aceon Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.