Dichloralphenazone

19 interactions 2 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Nalbuphine Injection Buprenorphine Butorphanol Injection Butorphanol Nasal Spray Fentanyl Transdermal Patch Hydromorphone Rectal
18 Major 1 Moderate
All (19) Major (18) Moderate (1)

Major

Dichloralphenazone Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of respiratory and CNS depression Details Dichloralphenazone Buprenorphine Belbuca Explained An increased risk of respiratory depression and CNS depression Details Dichloralphenazone Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Dichloralphenazone Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Dichloralphenazone Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Dichloralphenazone Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Dichloralphenazone Diazepam Nasal Spray Valtoco Increased risk of CNS depression Details Dichloralphenazone Diazepam Rectal Diastat Increased risk of CNS depression Details Dichloralphenazone Esketamine Nasal Spray Spravato Increased risk of sedation Details Dichloralphenazone Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Dichloralphenazone Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression Details Dichloralphenazone Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression Details Dichloralphenazone Lacosamide Injection Motpoly An increased risk of CNS depression Details Dichloralphenazone Levodopa Oral Inhalation Inbrija An increased risk of CNS depression Details Dichloralphenazone Metoclopramide Injection Gimoti Increased risk of CNS depression Details Dichloralphenazone Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Dichloralphenazone Morphine Injection Astramorph® PF Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Dichloralphenazone Nalbuphine Injection Nubain® Increased risk of respiratory and CNS depression Details

Moderate

Dichloralphenazone Clonidine Transdermal Patch Catapres An increased risk of sedation and somnolence Details

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