Bosutinib Interactions
Bosutinib is used to treat a certain type of chronic myeloid leukemia (CML; a type of cancer of the white blood cells), including treatment in adults who have been recently found to have this condition and in those who can no longer benefit from other medications for CML or who cannot take these medications because of side effects. Bosutinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.
Brand Names Associated with Bosutinib
- Bosulif®
- Bosutinib
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- Contraindicated
- Major
- Omeprazole
- Imatinib
- Esomeprazole
- Clarithromycin
- Pantoprazole
- Diltiazem
- Lansoprazole
- Ciprofloxacin
- Adagrasib
- Adenovirus Vaccine
- Amprenavir
- Aprepitant
- Atazanavir
- Bacillus of Calmette and Guerin Vaccine, Live
- Belzutifan
- Boceprevir
- Carbamazepine
- Ceritinib
- Cholera Vaccine, Live
- Cimetidine
- Clofazimine
- Cobicistat
- Conivaptan
- Crizotinib
- Cyclosporine
- Dabrafenib
- Darunavir
- Dengue Tetravalent Vaccine, Live
- Dexlansoprazole
- Dronedarone
- Duvelisib
- Enzalutamide
- Erythromycin
- Fedratinib
- Fexinidazole
- Fluconazole
- Fluvoxamine
- Fosamprenavir
- Fosnetupitant
- Fosphenytoin
- Idelalisib
- Indinavir
- Influenza Virus Vaccine, Live
- Itraconazole
- Ivosidenib
- Ketoconazole
- Larotrectinib
- Lefamulin
- Lenacapavir
- Letermovir
- Lonafarnib
- Lorlatinib
- Lumacaftor
- Mavacamten
- Mifepristone
- Mitotane
- Nefazodone
- Nelfinavir
- Netupitant
- Nilotinib
- Olutasidenib
- Omaveloxolone
- Pacritinib
- Phenobarbital
- Phenytoin
- Pirtobrutinib
- Poliovirus Vaccine, Live
- Posaconazole
- Primidone
- Rabeprazole
- Ribociclib
- Rifampin
- Rifapentine
- Ritlecitinib
- Ritonavir
- Saquinavir
- Schisandra sphenanthera
- Smallpox Vaccine
- St John's Wort
- Telaprevir
- Telithromycin
- Tocilizumab
- Trofinetide
- Troleandomycin
- Tucatinib
- Typhoid Vaccine, Live
- Verapamil
- Voriconazole
- Voxelotor
- Yellow Fever Vaccine
- Adenovirus Vaccine, Live
- Asciminib
- Avacopan
- Daridorexant
- Ebola Zaire Vaccine, Live
- Enasidenib
- Erdafitinib
- Lanreotide
- Mitapivat
- Mobocertinib
- Nirogacestat
- Octreotide
- Palbociclib
- Repotrectinib
- Selpercatinib
- Smallpox Monkeypox Vaccine, Live Non-Replicating
- Sotorasib
- Taurursodiol
- Vonoprazan
- Moderate
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What Do The Severity Ratings Mean?
Contraindicated
These drugs, generally, should not be used together simultaneously due to the high risk of severe adverse effects. Combining these medications can lead to dangerous health outcomes and should be strictly avoided unless otherwise instructed by your provider.
Major
This interaction could result in very serious and potentially life-threatening consequences. If you are taking this drug combination, it is very important to be under close medical supervision to minimize severe side effects and ensure your safety. It may be necessary to change a medication or dosage to prevent harm.
Moderate
This interaction has the potential to worsen your medical condition or alter the effectiveness of your treatment. It's important that you are monitored closely and you potentially may need to make adjustments in your treatment plan or drug dosage to maintain optimal health.
Minor
While this interaction is unlikely to cause significant problems, it could intensify side effects or reduce the effectiveness of one or both medications. Monitoring for changes in symptoms and your condition is recommended, and adjustments may be made if needed to manage any increased or more pronounced side effects.
Disclaimer: The information provided on this page is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional regarding your specific circumstances and medical conditions.
Drug interaction information is compilated from several drug compendia, including:
- Gold Standard Drug Database
- Micromedix
- Lexicomp
- PubMed
The information posted is fact-checked by HelloPharmacist clinicians and reviewed quarterly.