Dronedarone

146 interactions 12 explained in plain English

Also sold as: Multaq

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Galantamine Octreotide Injection Cyclosporine Ophthalmic Relugolix Ofloxacin Otic Foscarnet Injection

66 Contraindicated 73 Major 7 Moderate

All (146) Contraindicated (66) Major (73) Moderate (7)

Contraindicated

Dronedarone Amitriptyline Elavil Explained Increased risk of QT interval prolongation Details Dronedarone Sertraline Explained Increased risk of QT interval prolongation Details Dronedarone Buprenorphine Belbuca Explained Increased risk of QT interval prolongation Details Dronedarone Relugolix Orgovyx Explained Increased relugolix exposure and an increased risk of QT interval prolongation Details Dronedarone Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of colchicine toxicity Details Dronedarone Amisulpride Injection Barhemsys Increased risk of QT interval prolongation Details Dronedarone Arsenic Trioxide Trisenox Increased risk of QT interval prolongation Details Dronedarone Aripiprazole Injection Abilify Increased risk of QT interval prolongation Details Dronedarone Arsenic Trioxide Injection Trisenox Increased risk of QT interval prolongation Details Dronedarone Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Dronedarone Azithromycin AzaSite Increased risk of QT interval prolongation Details Dronedarone Alfuzosin UroXatral Increased risk of QT interval prolongation Details Dronedarone Anagrelide Agrylin Increased risk of QT interval prolongation Details Dronedarone Bedaquiline Sirturo Increased risk of QT interval prolongation Details Dronedarone Chloroquine Aralen® Increased risk of QT interval prolongation Details Dronedarone Cyclosporine Injection Atopica Increased dronedarone plasma concentrations Details Dronedarone Cyclosporine Ophthalmic Cequa Increased dronedarone plasma concentrations Details Dronedarone Dasatinib Phyrago Increased risk of QT interval prolongation Details Dronedarone Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Dronedarone Deutetrabenazine Austedo Increased risk of QT interval prolongation Details Dronedarone Disopyramide Norpace Increased risk of QT interval prolongation Details Dronedarone Dofetilide Tikosyn Increased risk of QT interval prolongation Details Dronedarone Dolasetron Anzemet Increased risk of QT interval prolongation Details Dronedarone Dolasetron Injection Anzemet Increased risk of QT interval prolongation Details Dronedarone Encorafenib Braftovi An increased risk of QT interval prolongation, increased encorafenib exposure, an increased risk of encorafenib-related adverse re... Details Dronedarone Entrectinib Rozlytrek Increased risk of QT interval prolongation Details Dronedarone Eribulin Injection Halaven Increased risk of QT interval prolongation Details Dronedarone Famotidine Calmicid Increased risk of QT interval prolongation Details Dronedarone Famotidine Injection Calmicid Increased risk of QT interval prolongation Details Dronedarone Felbamate Felbatol Increased risk of QT interval prolongation Details Dronedarone Flecainide Tambocor® Increased risk of QT interval prolongation Details Dronedarone Foscarnet Injection Foscavir Increased risk of QT interval prolongation Details Dronedarone Fostemsavir Rukobia Increased risk of QT interval prolongation Details Dronedarone Galantamine Razadyne Increased risk of QT interval prolongation Details Dronedarone Gatifloxacin Ophthalmic Zymar® Increased risk of QT interval prolongation Details Dronedarone Gemifloxacin Factive Increased risk of QT interval prolongation Details Dronedarone Glasdegib Daurismo Increased risk of QT interval prolongation Details Dronedarone Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Dronedarone Granisetron Transdermal Patch Sancuso Increased risk of QT interval prolongation Details Dronedarone Granisetron Injection Granisol Increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.