Dexketoprofen

91 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Dexketoprofen Amitriptyline Elavil Explained An increased risk of bleeding Details Dexketoprofen Sertraline Explained An increased risk of bleeding Details Dexketoprofen Apixaban Eliquis Explained An increased risk of bleeding Details Dexketoprofen Aspirin Acuprin® An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Dexketoprofen Aspirin Rectal Aspirin An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Dexketoprofen Betrixaban Bevyxxa® An increased risk of bleeding Details Dexketoprofen Anagrelide Agrylin An increased risk of bleeding Details Dexketoprofen Bromfenac Ophthalmic Bromday® Increased risk of bleeding Details Dexketoprofen Budesonide Entocort Increased risk of gastrointestinal ulcer or bleeding Details Dexketoprofen Budesonide Nasal Spray Rhinocort Increased risk of gastrointestinal ulcer or bleeding Details Dexketoprofen Budesonide Oral Inhalation Pulmicort Increased risk of gastrointestinal ulcer or bleeding Details Dexketoprofen Clopidogrel Plavix An increased risk of bleeding Details Dexketoprofen Cyclosporine Injection Atopica An increased risk of cycloSPORINE nephrotoxicity Details Dexketoprofen Cyclosporine Ophthalmic Cequa An increased risk of cycloSPORINE nephrotoxicity Details Dexketoprofen Dabigatran Pradaxa® An increased risk of bleeding Details Dexketoprofen Dabigatran Etexilate An increased risk of bleeding Details Dexketoprofen Dalteparin Injection Fragmin An increased risk of bleeding Details Dexketoprofen Deflazacort Emflaza Increased risk of gastrointestinal ulcer or bleeding Details Dexketoprofen Dexamethasone Injection Decadron Increased risk of gastrointestinal ulcer or bleeding Details Dexketoprofen Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Increased risk of gastrointestinal ulcer or bleeding Details Dexketoprofen Diclofenac Ophthalmic Voltaren® Eye Drops Increased risk of bleeding Details Dexketoprofen Diclofenac Topical (Actinic Keratosis) Pennsaid Increased risk of bleeding Details Dexketoprofen Diclofenac Topical (Arthritis Pain) Pennsaid® Increased risk of bleeding Details Dexketoprofen Diclofenac Transdermal Patch Flector Increased risk of bleeding Details Dexketoprofen Digoxin Cardoxin® Increased digoxin exposure and prolonged half-life of digoxin Details Dexketoprofen Dipyridamole Permole® An increased risk of bleeding Details Dexketoprofen Edoxaban Savaysa An increased risk of bleeding Details Dexketoprofen Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Dexketoprofen Enoxaparin Lovenox An increased risk of bleeding Details Dexketoprofen Enoxaparin Injection Lovenox An increased risk of bleeding Details Dexketoprofen Epoprostenol Flolan An increased risk of bleeding Details Dexketoprofen Etodolac Lodine Increased risk of bleeding Details Dexketoprofen Fenoprofen Fenopron Increased risk of bleeding Details Dexketoprofen Flurbiprofen Ansaid Increased risk of bleeding Details Dexketoprofen Flurbiprofen Ophthalmic Ocufen Increased risk of bleeding Details Dexketoprofen Fondaparinux Arixtra An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.