Mechlorethamine Topical

16 interactions 147 cited references
Also sold as: Valchlor Valchlor®
About Mechlorethamine Topical

Mechlorethamine gel is an alkylating agent chemotherapy used to treat early-stage cutaneous T-cell lymphoma skin cancer. Read the full Mechlorethamine Topical drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Typhoid Vaccine Measles Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Mumps Virus Vaccine, Live Varicella Virus Vaccine, Live
9 Contraindicated 7 Major
All (16) Contraindicated (9) Major (7)

Contraindicated

Mechlorethamine Topical Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Mechlorethamine Topical Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Mechlorethamine Topical Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Mechlorethamine Topical Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Mechlorethamine Topical Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Mechlorethamine Topical Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Mechlorethamine Topical Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Mechlorethamine Topical Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Mechlorethamine Topical Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Mechlorethamine Topical Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Mechlorethamine Topical Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Mechlorethamine Topical Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Mechlorethamine Topical Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Mechlorethamine Topical Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Mechlorethamine Topical Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details Mechlorethamine Topical Warfarin Coumadin Increased risk for elevated INR and subsequent bleeding Details

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