Eravacycline Injection

60 interactions 255 cited references

Also sold as: Xerava Xerava®

About Eravacycline Injection

Eravacycline injection used to treat infections of the abdomen (stomach area). Eravacycline injection is in a class of medications called tetracycline antibiotics. It works by killing bacteria that cause infection. Antibiotics such as eravacycline injection will not work for colds, flu, or other viral infections. Using… Read the full Eravacycline Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acitretin Ensitrelvir Abametapir Amoxicillin Ampicillin Apalutamide

2 Contraindicated 51 Major 7 Moderate

All (60) Contraindicated (2) Major (51) Moderate (7)

Contraindicated

Eravacycline Injection Acitretin Soriatane® An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Eravacycline Injection Ensitrelvir Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details

Major

Eravacycline Injection Abametapir Increased exposure of CYP3A4 substrate Details Eravacycline Injection Amoxicillin Amoxi Drop Decreased antibacterial effectiveness Details Eravacycline Injection Ampicillin Amcill® Decreased antibacterial effectiveness Details Eravacycline Injection Apalutamide Erleada Reduced CYP3A4 substrate exposure Details Eravacycline Injection Avacopan Tavneos Increased CYP3A4 substrate exposure Details Eravacycline Injection Bacampicillin Decreased antibacterial effectiveness Details Eravacycline Injection Bexarotene Targretin An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Eravacycline Injection Carbamazepine Carbatrol Reduced eravacycline concentrations and efficacy Details Eravacycline Injection Clarithromycin Biaxin Increased exposure of CYP3A4 substrate and risk for toxicity Details Eravacycline Injection Cloxacillin Decreased antibacterial effectiveness Details Eravacycline Injection Conivaptan Vaprisol Increased CYP3A substrate exposure Details Eravacycline Injection Dicloxacillin Decreased antibacterial effectiveness Details Eravacycline Injection Enzalutamide Xtandi Reduced eravacycline concentrations and efficacy Details Eravacycline Injection Erythromycin Erythrocin Stearate Increased CYP3A4 substrate exposure and an increased risk of CYP3A4-substrate-related adverse effects Details Eravacycline Injection Ethinyl Estradiol Reduced ethinyl estradiol exposure, reduced efficacy of ethinyl estradiol and an increased risk of breakthrough bleeding and/or co... Details Eravacycline Injection Etretinate An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Eravacycline Injection Fedratinib Inrebic Increased CYP3A4 substrate exposure Details Eravacycline Injection Fexinidazole An increased CYP3A4 substrate exposure Details Eravacycline Injection Fosphenytoin Cerebyx Reduced eravacycline concentrations and efficacy Details Eravacycline Injection Isotretinoin Absorica An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Eravacycline Injection Itraconazole Sporanox Increased CYP3A4 substrate exposure and an increased risk of CYP3A4 substrate-related adverse effects Details Eravacycline Injection Letermovir Prevymis Increased CYP3A substrate exposure Details Eravacycline Injection Levonorgestrel After banger Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Eravacycline Injection Lumacaftor Reduced eravacycline concentrations and efficacy Details Eravacycline Injection Magnesium Sulfate May reduce absorption of tetracycline antibiotics Details Eravacycline Injection Methicillin Decreased antibacterial effectiveness Details Eravacycline Injection Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Eravacycline Injection Mifepristone Korlym Increased CYP3A4 substrate exposure Details Eravacycline Injection Mitotane Lysodren Reduced eravacycline concentrations and efficacy Details Eravacycline Injection Nafcillin Decreased antibacterial effectiveness Details Eravacycline Injection Omaveloxolone Skyclarys Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Eravacycline Injection Oxacillin Decreased antibacterial effectiveness Details Eravacycline Injection Palovarotene Sohonos Increased risk of benign intracranial hypertension (pseudotumor cerebri) Details Eravacycline Injection Penicillin G Decreased antibacterial effectiveness Details Eravacycline Injection Penicillin G Benzathine Decreased antibacterial effectiveness Details Eravacycline Injection Penicillin G Procaine Decreased antibacterial effectiveness Details Eravacycline Injection Penicillin V Decreased antibacterial effectiveness Details Eravacycline Injection Phenobarbital Fidoquel Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.