Tan-Shen

22 interactions
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Defibrotide Injection Fondaparinux Fondaparinux Injection Heparin Heparin Injection
5 Major 13 Moderate 4 Minor
All (22) Major (5) Moderate (13) Minor (4)

Major

Tan-Shen Defibrotide Injection Defitelio Increased risk of bleeding Details Tan-Shen Fondaparinux Arixtra Increased risk of bleeding Details Tan-Shen Fondaparinux Injection Arixtra Increased risk of bleeding Details Tan-Shen Heparin Increased risk of bleeding Details Tan-Shen Heparin Injection Lipo-Hepin® Increased risk of bleeding Details

Moderate

Tan-Shen Aspirin Acuprin® Increased free salicylate serum concentration and decreased tan-shen (Danshen) concentration Details Tan-Shen Aspirin Rectal Aspirin Increased free salicylate serum concentration and decreased tan-shen (Danshen) concentration Details Tan-Shen Anagrelide Agrylin Increased risk of bleeding Details Tan-Shen Becaplermin Topical Regranex Increased risk of bleeding Details Tan-Shen Clopidogrel Plavix Increased risk of bleeding Details Tan-Shen Dalteparin Injection Fragmin Increased risk of bleeding Details Tan-Shen Dipyridamole Permole® Increased risk of bleeding Details Tan-Shen Enoxaparin Lovenox Increased risk of bleeding Details Tan-Shen Enoxaparin Injection Lovenox Increased risk of bleeding Details Tan-Shen Epoprostenol Flolan Increased risk of bleeding Details Tan-Shen Iloprost Aurlumyn Increased risk of bleeding Details Tan-Shen Mesalamine Apriso Increased free salicylate serum concentration and decreased tan-shen (Danshen) concentration Details Tan-Shen Mesalamine Rectal Canasa Increased free salicylate serum concentration and decreased tan-shen (Danshen) concentration Details

Minor

Tan-Shen Diazepam Nasal Spray Valtoco Increased risk of central nervous system depression Details Tan-Shen Diazepam Rectal Diastat Increased risk of central nervous system depression Details Tan-Shen Midazolam Nasal Spray Nayzilam Increased risk of central nervous system depression Details Tan-Shen Midazolam Injection Nayzilam Increased risk of central nervous system depression Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.