Psyllium

Name: Psyllium Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

8 interactions 1 explained in plain English

Also sold as: Alramucil® Cilium® Fiberall® Genfiber® Hydrocil Hydrocil® Konsyl Konsyl® Maalox Daily Fiber Therapy® Metamucil Metamucil® Mucilin Natural Fiber Therapy® Natural Vegetable® Perdiem Fiber® Reguloid Reguloid® Serutan® Syllact® Uni-Laxative® V-Lax® Wal-Mucil

About Psyllium

Psyllium is a bulk-forming laxative used to treat constipation by absorbing liquid in the intestines to form easier-to-pass stools. Read the full Psyllium drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

8 Moderate

All (8) Moderate (8)

Moderate

Psyllium Acarbose Prandase® Explained Increased risk of hypoglycemia Details Psyllium Glimepiride Amaryl Increased risk of hypoglycemia Details Psyllium Glipizide Glucotrol Increased risk of hypoglycemia Details Psyllium Insulin Glulisine (Rdna Origin) Injection Apidra Increased risk of hypoglycemia Details Psyllium Lithium Carbonate Lithobid Decreased plasma levels and effectiveness of lithium Details Psyllium Metformin Fortamet® Increased risk of hypoglycemia Details Psyllium Miglitol Glyset® Increased risk of hypoglycemia Details Psyllium Nateglinide Starlix® Increased risk of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.