Levonorgestrel

Contraindicated

Levonorgestrel Dasabuvir An increased risk of ALT elevation Details Levonorgestrel Fezolinetant Increased fezolinetant exposure Details Levonorgestrel Ombitasvir An increased risk of ALT elevation Details Levonorgestrel Paritaprevir An increased risk of ALT elevation Details Levonorgestrel Ritonavir Norvir An increased risk of ALT elevation, reduced progestin exposure and reduced efficacy of contraceptive Details Levonorgestrel Tranexamic Acid Cyklokapron An increased risk of thrombotic events Details

Major

Levonorgestrel Isotretinoin Absorica Decreased effectiveness of hormonal contraceptives Details Levonorgestrel Amoxicillin Amoxi Drop Reduced efficacy of oral contraceptive Details Levonorgestrel Ampicillin Amcill® Decreased contraceptive effectiveness Details Levonorgestrel Ampicillin Injection Omnipen-N® Decreased contraceptive effectiveness Details Levonorgestrel Bexarotene Targretin Decreased contraceptive effectiveness Details Levonorgestrel Bexarotene Topical Targretin Decreased contraceptive effectiveness Details Levonorgestrel Cefaclor Ceclor® Decreased contraceptive effectiveness Details Levonorgestrel Cefadroxil Duricef® Decreased contraceptive effectiveness Details Levonorgestrel Cefdinir Omnicef® Decreased contraceptive effectiveness Details Levonorgestrel Cefixime Suprax Decreased contraceptive effectiveness Details Levonorgestrel Cefprozil Cefzil® Decreased contraceptive effectiveness Details Levonorgestrel Ceftazidime Injection Fortaz Decreased contraceptive effectiveness Details Levonorgestrel Cefuroxime Injection Kefurox® Decreased contraceptive effectiveness Details Levonorgestrel Colesevelam Welchol Decreased contraceptive effectiveness Details Levonorgestrel Cyclosporine Injection Atopica Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Levonorgestrel Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Levonorgestrel Demeclocycline Declomycin® Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Levonorgestrel Dexamethasone Injection Decadron Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Doxycycline Injection Acticlate Reduced efficacy of oral contraceptive Details Levonorgestrel Enasidenib Idhifa Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Encorafenib Braftovi Reduced hormonal contraceptives exposure and reduced efficacy of hormonal contraceptives Details Levonorgestrel Eravacycline Injection Xerava Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Levonorgestrel Exenatide Injection Bydureon Reduced oral contraceptives absorption and reduced efficacy of oral contraceptives Details Levonorgestrel Felbamate Felbatol Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding or contraceptiv... Details Levonorgestrel Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Levonorgestrel Hydrocortisone Ala-Cort Altered (reduced/increased) hydrocortisone exposure, reduced efficacy of hydrocortisone and an increased risk of hydrocortisone-re... Details Levonorgestrel Hydrocortisone Injection A-Hydrocort® Altered (reduced/increased) hydrocortisone exposure, reduced efficacy of hydrocortisone and an increased risk of hydrocortisone-re... Details Levonorgestrel Ketoconazole Topical Extina® Foam Increased levonorgestrel exposure Details Levonorgestrel Alfentanil Increased ALfentanil exposure, an increased risk of ALfentanil-related adverse reactions and/or prolonged effects, which may exace... Details Levonorgestrel Amobarbital Amytal Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding or contraceptiv... Details Levonorgestrel Amprenavir Reduced amprenavir exposure, altered hormonal levels, loss of contraceptive efficacy, and an increased risk of liver enzyme elevat... Details Levonorgestrel Apalutamide Erleada Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Levonorgestrel Aprepitant Aponvie Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and an increased risk of breakthrough bleedin... Details