Periciazine

29 interactions 2 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Metoclopramide Injection Metoclopramide Nasal Spray Midazolam Nasal Spray Nalbuphine Injection Fentanyl Transdermal Patch Lacosamide Injection
2 Contraindicated 25 Major 2 Moderate
All (29) Contraindicated (2) Major (25) Moderate (2)

Contraindicated

Periciazine Metoclopramide Injection Gimoti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Periciazine Metoclopramide Nasal Spray Gimoti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details

Major

Periciazine Acetaminophen And Codeine Capital® & Codeine Explained Risk of enhanced CNS depression Details Periciazine Buprenorphine Belbuca Explained An increased risk of respiratory depression and CNS depression Details Periciazine Aripiprazole Injection Abilify Risk of enhanced CNS depression Details Periciazine Asenapine Transdermal Patch Secuado Risk of enhanced CNS depression Details Periciazine Cabergoline Dostinex® Reduced efficacy of cabergoline and reduced efficacy of dopamine-2 receptors Details Periciazine Butorphanol Injection Butorphic Risk of enhanced CNS depression Details Periciazine Butorphanol Nasal Spray Stadol® NS Risk of enhanced CNS depression Details Periciazine Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Periciazine Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Periciazine Diazepam Nasal Spray Valtoco Risk of enhanced CNS depression Details Periciazine Diazepam Rectal Diastat Risk of enhanced CNS depression Details Periciazine Diphenhydramine Injection Banophen Risk of enhanced CNS depression Details Periciazine Diphenhydramine Topical Afterbite with Antihistamine Risk of enhanced CNS depression Details Periciazine Esketamine Nasal Spray Spravato Increased risk of sedation Details Periciazine Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Periciazine Hydromorphone Injection Dilaudid Risk of enhanced CNS depression Details Periciazine Hydromorphone Rectal available generically Risk of enhanced CNS depression Details Periciazine Hydroxychloroquine Plaquenil An increased risk of seizures Details Periciazine Lacosamide Injection Motpoly An increased risk of CNS depression Details Periciazine Levodopa Oral Inhalation Inbrija Reduce efficacy of levodopa (foslevodopa), an increased risk of exacerbating psychosis [or symptoms of Parkinson's disease: delusi... Details Periciazine Lithium Carbonate Lithobid Weakness, dyskinesias, increased extrapyramidal symptoms, encephalopathy, and brain damage Details Periciazine Midazolam Nasal Spray Nayzilam Risk of enhanced CNS depression Details Periciazine Midazolam Injection Nayzilam Risk of enhanced CNS depression Details Periciazine Morphine Injection Astramorph® PF Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Periciazine Nalbuphine Injection Nubain® Risk of enhanced CNS depression Details

Moderate

Periciazine Clonidine Transdermal Patch Catapres An increased risk of sedation and somnolence Details Periciazine Metformin Fortamet® An increased risk of hyperglycemia and potential loss of glycemic control Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.