Pixantrone

23 interactions 2 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Nabumetone Amitriptyline Estradiol Topical Chloroquine Naproxen Ketoconazole Topical
23 Major
All (23) Major (23)

Major

Pixantrone Acetaminophen And Codeine Capital® & Codeine Explained Increased CYP1A2 substrate exposure Details Pixantrone Amitriptyline Elavil Explained Increased CYP1A2 substrate exposure Details Pixantrone Acetaminophen Acephen Increased CYP1A2 substrate exposure Details Pixantrone Acetaminophen Injection Acephen Increased CYP1A2 substrate exposure Details Pixantrone Acetaminophen Rectal Acephen Increased CYP1A2 substrate exposure Details Pixantrone Azithromycin AzaSite Increased exposure to pixantrone Details Pixantrone Abiraterone Abirtega Increased exposure to pixantrone Details Pixantrone Anagrelide Agrylin Increased anagrelide exposure Details Pixantrone Captopril Capoten® Increased exposure to pixantrone Details Pixantrone Chloroquine Aralen® Increased exposure of CYP2C8 substrates Details Pixantrone Cyclosporine Injection Atopica Increased exposure to pixantrone Details Pixantrone Cyclosporine Ophthalmic Cequa Increased exposure to pixantrone Details Pixantrone Estradiol Delestrogen Increased CYP1A2 substrate exposure Details Pixantrone Estradiol Topical Divigel Increased CYP1A2 substrate exposure Details Pixantrone Estradiol Transdermal Patch Alora® Increased CYP1A2 substrate exposure Details Pixantrone Felodipine Plendil® Increased exposure to pixantrone Details Pixantrone Fluvastatin Lescol Increased exposure of CYP2C8 substrates Details Pixantrone Ketoconazole Topical Extina® Foam Increased exposure to pixantrone Details Pixantrone Margetuximab-Cmkb Injection Margenza Increased risk of cardiac dysfunction Details Pixantrone Mexiletine Mexitil® Increased CYP1A2 substrate exposure Details Pixantrone Montelukast Singulair Increased exposure of CYP2C8 substrates Details Pixantrone Nabumetone Relafen Increased CYP1A2 substrate exposure Details Pixantrone Naproxen Aleve Increased CYP1A2 substrate exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.