Alvimopan

Name: Alvimopan Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

5 interactions 21 cited references

Also sold as: Entereg Entereg®

About Alvimopan

Alvimopan is used to help the bowel recover more quickly after bowel surgery, so that you can eat solid foods and have regular bowel movements. Alvimopan is in a class of medications called peripherally acting mu-opioid receptor antagonists. It works by protecting the bowel from the constipation effects of opioid (narc… Read the full Alvimopan drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Morphine Morphine Sulfate Liposome Naldemedine Naloxegol Morphine Injection

5 Major

All (5) Major (5)

Major

Alvimopan Morphine Decreased opioid efficacy and precipitation of opioid withdrawal Details Alvimopan Morphine Sulfate Liposome Decreased opioid efficacy and precipitation of opioid withdrawal Details Alvimopan Naldemedine Symproic Increased risk of opioid withdrawal Details Alvimopan Naloxegol Movantik Risk of opioid withdrawal Details Alvimopan Morphine Injection Astramorph® PF Decreased opioid efficacy and precipitation of opioid withdrawal Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.