Loratadine
29 interactions 437 cited referencesAn antihistamine used to relieve allergy symptoms like sneezing, runny nose, itchy eyes, and itching from hives. Read the full Loratadine drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Contraindicated
Loratadine Ensitrelvir Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details Loratadine Mavorixafor Xolremdi Increased CYP2D6 substrate exposure and an increased risk of CYP2D6 substrate-related adverse events DetailsMajor
Loratadine Sertraline Increased CYP2D6 substrate exposure Details Loratadine Ketoconazole Topical Extina® Foam Increased loratadine exposure Details Loratadine Letermovir Injection Prevymis Increased CYP3A substrate exposure Details Loratadine Amiodarone Nexterone Increased risk of QT interval prolongation and torsade de pointes Details Loratadine Apalutamide Erleada Reduced CYP3A4 substrate exposure Details Loratadine Avacopan Tavneos Increased CYP3A4 substrate exposure Details Loratadine Carbamazepine Carbatrol Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Loratadine Clarithromycin Biaxin Increased exposure of CYP3A4 substrate and risk for toxicity Details Loratadine Conivaptan Vaprisol Increased CYP3A substrate exposure Details Loratadine Erythromycin Erythrocin Stearate Increased CYP3A4 substrate exposure and an increased risk of CYP3A4-substrate-related adverse effects Details Loratadine Itraconazole Sporanox Increased CYP3A4 substrate exposure and an increased risk of CYP3A4 substrate-related adverse effects Details Loratadine Ketoconazole Extina Increased loratadine exposure Details Loratadine Letermovir Prevymis Increased CYP3A substrate exposure Details Loratadine Lumefantrine Increased CYP2D6 substrate exposure and an increased risk of CYP2D6 substrate-related adverse reactions Details Loratadine Mifepristone Korlym Increased CYP3A4 substrate exposure Details Loratadine Omaveloxolone Skyclarys Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Loratadine Paroxetine Paxil Increased CYP2D6 substrate exposure Details Loratadine Pitolisant Wakix Reduced efficacy of pitolisant Details Loratadine Ranolazine Aspruzyo Increased CYP2D6 substrates exposure Details Loratadine Relacorilant Lifyorli Increased CYP3A4 substrate exposure and an increased risk of CYP3A4-substrate-related adverse reactions Details Loratadine Tazemetostat Tazverik Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Loratadine Voriconazole Vfend Increased CYP3A4 substrates exposure and an increased efficacy of CYP3A4 substrates-related adverse effects DetailsModerate
Loratadine Artemether Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Loratadine Kratom Increased CYP3A substrate exposure Details Loratadine Mavacamten Camzyos Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Loratadine Rilzabrutinib Wayrilz Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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