Loratadine

Name: Loratadine Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

29 interactions 437 cited references

Also sold as: Agistam® Alavert Alavert® Claritin Claritin® Clear-Atadine® Cleartime Indoor & Outdoor Allergies Dimetapp® ND Loradamed Tavist Non-Sedating Tavist® Non-Sedating Wal-itin Wal-itin® Wal-vert

About Loratadine

An antihistamine used to relieve allergy symptoms like sneezing, runny nose, itchy eyes, and itching from hives. Read the full Loratadine drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ensitrelvir Mavorixafor Letermovir Injection Amiodarone Apalutamide Avacopan

2 Contraindicated 22 Major 4 Moderate 1 Minor

All (29) Contraindicated (2) Major (22) Moderate (4) Minor (1)

Contraindicated

Loratadine Ensitrelvir Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details Loratadine Mavorixafor Xolremdi Increased CYP2D6 substrate exposure and an increased risk of CYP2D6 substrate-related adverse events Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.